KLK7-IN-1
KLK7-IN-1 is a KLK7 inhibitor with an IC50 of 43.3 μM. KLK7-IN-1 is used in studies of kallikrein-driven pathologies.
For research use only. We do not sell to patients.
- CAS No.: 63124-11-8
- Formula: C10H6N2O
- Molecular Weight:170.17
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
IC50 & Target
[1]|
KLK7 43.3 μM (IC50) |
In Vitro
KLK7-IN-1 (Compound 38) (100 μM; 15 min) acts as a ligand-efficient inhibitor of recombinant hKLK7 with an IC50 of 43.3 μM and low cross-reactivity with other kallikreins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Chemical Information
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CAS No. 63124-11-8
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Molecular Weight 170.17
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Formula C10H6N2O
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SMILES
O=C(N1)C=CC2=C1C=CC(C#N)=C2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
KLK7-IN-1 Related Classifications
HY-W556970 Related Classifications
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