2. Gene
  3. ALDH1A1 - aldehyde dehydrogenase 1 family, member A1 Gene

ALDH1A1 - aldehyde dehydrogenase 1 family, member A1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Ahd2; Aldh1; Aldh2

Gene ID: 24188 | Gene type: protein coding

About ALDH1A1

Primary_assembly 1: 218,042,127-218,152,961 forward strand.mRatBN7.2:CM026974.1

This gene has 2 transcripts (splice variants), 200 orthologues, 20 paralogues and is associated with 53 phenotypes. Biased expression in Kidney (RPKM 2289.1), Testes (RPKM 1535.4) and 6 other tissues.

Summary

Enables benzaldehyde dehydrogenase (NAD+) activity; identical protein binding activity; and retinal dehydrogenase activity. Involved in several processes, including estrous cycle; maintenance of lens transparency; and retinoic acid metabolic process. Located in cytoplasm and nucleus. Orthologous to human ALDH1A1 (aldehyde dehydrogenase 1 family member A1). [provided by Alliance of Genome Resources, Apr 2022]

ALDH1A1 Products(1)

mRNA Protein Name
NM_022407.3 NP_071852.2 aldehyde dehydrogenase 1A1

ALDH1A1 Protein Structure

ALDH_F1AB_F2_RALDH1

ALDH_F1AB_F2_RALDH1: cd07141 (33 - 513)

  • 0
  • 100
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  • 520 a.a.
Protein Preferred Names Protein Names

aldehyde dehydrogenase 1A1

retinal dehydrogenase 1

3-deoxyglucosone dehydrogenase

ALDH-E1

ALHDII

RALDH 1

aldehyde dehydrogenase 1, subfamily A1

aldehyde dehydrogenase 2

aldehyde dehydrogenase family 1 member A1

aldehyde dehydrogenase family 1, subfamily A1

aldehyde dehydrogenase, cytosolic

ralDH1

Related Agents

Pre-clinical Phase
Bioactive Molecules (24)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-138097 α-NETA ≥98.0% Unkown
HY-18768 NCT-501 Inhibitor 99.84% Unkown
HY-148466 IGUANA-1 Inhibitor 98.88% Unkown
HY-123621 GNE-375 Inhibitor 99.81% Unkown
HY-135841 CM10 Inhibitor 98.07% Unkown
HY-112277 NCT-505 Inhibitor 98.41% Unkown
HY-112278 NCT-506 Inhibitor 99.44% Unkown
HY-146683 KS106 99.31% Unkown
HY-110294 CM037 Inhibitor 99.06% Unkown
HY-126003 ALDH1A1-IN-2 Inhibitor 99.48% Unkown
HY-146682 KS100 99.61% Unkown
HY-157567 FSI-TN42 Inhibitor 98.05% Unkown
HY-146240 ALDH1A1-IN-3 Inhibitor / Unkown
HY-148243 IGUANA-1 free base Inhibitor / Unkown
HY-155816 PROTAC NSD3 degrader-1 / Unkown
HY-157872 ALDH1A1-IN-4 Inhibitor / Unkown
HY-158026 ALDH1A1-IN-5 Inhibitor / Unkown
HY-18768A NCT-501 hydrochloride Inhibitor / Unkown
HY-RS00560 ALDH1A1 Human Pre-designed siRNA Set A / Unkown
HY-RS00561 Aldh1a1 Mouse Pre-designed siRNA Set A / Unkown
HY-RS00562 ALDH1A1 Rat Pre-designed siRNA Set A / Unkown
HY-RS00565 ALDH1B1 Human Pre-designed siRNA Set A / Unkown
HY-RS00566 ALDH1L1 Human Pre-designed siRNA Set A / Unkown
HY-122912 ALDH1A inhibitor 673A / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens ALDH1A1 NCBI NCBI:216