IGUANA-1 free base
Based on 1 publication(s) in Google Scholar
IGUANA-1 free base (STL5-T-0057) is an selective ALDH1 B1 inhibitor with an IC50 value of 30 nM. IGUANA-1 free base inhibits cell growth of SW480 cells in adherent and spheroid conditions with IC50 values of 2.46 and 0.39 μM, respectively. IGUANA-1 free base can be used for the research of cancer.
For research use only. We do not sell to patients.
- Purity: 99.69%
- CAS No.: 2756014-24-9
- Formula: C26H24ClN3O2
- Molecular Weight:445.94
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Publications Citing Use of MedChemExpress (MCE) IGUANA-1 free base
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Biological Activity
IC50: 30 nM (ALDH1 B1), 2.46 μM (SW480, adherent), 0.39 μM (SW480, spheroid)[1]
IGUANA-1 free base (compound 68) (0-10 μM) inhibits ALDH1 B1 with an IC50 value of 30 nM[1]. IGUANA-1 free base (0.01-10 μM; 4-5 d) inhibits cell growth of HEK293T cells[1]. IGUANA-1 free base (0.01-10 μM) inhibits cell viability of SW480 cells in adherent and spheroid conditions with IC50 values of 2.46 and 0.39 μM, respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:HEK293T cell line
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Concentration:0.01-10 μM
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Incubation Time:4-5 d
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Result:Showed cell cytotoxicity to HEK293T cells with a GI50 value of 1.7 μM.
Chemical Information
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CAS No. 2756014-24-9
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Appearance Solid
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Molecular Weight 445.94
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Formula C26H24ClN3O2
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Color White to off-white
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SMILES
ClC1=CC(OC)=C(C2=CN(C3=NCCCN32)C4=CC=C(C5=C(OC)C=CC=C5)C=C4)C=C1
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Synonyms
STL5-T-0057
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Publications (1)
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Journal Impact Factor
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Most Recent
Purity & Documentation
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Data Sheet (272 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)