B2m - beta-2 microglobulin Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 24223

Summary

Predicted to enable MHC class II protein complex binding activity and protein homodimerization activity. Involved in response to cadmium ion and response to xenobiotic stimulus. Located in extracellular space. Biomarker of acute kidney failure; pyelonephritis; and ureteral obstruction. Human ortholog(s) of this gene implicated in arthritis; familial visceral amyloidosis; immunodeficiency 43; and inflammatory bowel disease. Orthologous to human B2M (beta-2-microglobulin). [provided by Alliance of Genome Resources, Apr 2022]

B2m Products (1)

mRNA Protein Name
NM_012512.2 NP_036644.1 beta-2-microglobulin precursor

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in response to cadmium ion IEP
IEP: Inferred from expression pattern
17327699 RGD
involved in response to xenobiotic stimulus IEP
IEP: Inferred from expression pattern
17211973 RGD
Cellular Component GO Annotation Evidence References Source
located in extracellular space IDA
IDA: Inferred from direct assay
3516141 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

beta-2-microglobulin

  • beta-2-microglobulin C-terminal fragment (55 AA)

Recombinant B2m Proteins

Cat. No. Product Name Accession Purity
HY-P74402 B2M/Beta-2 microglobulin Protein, Rat (HEK293, His, solution) P07151 (I21-M119) ≥ 95%, as determined by reducing SDS-PAGE.
HY-P75760 FCGRT-B2M Heterodimer Protein, Rat (HEK293, His, solution) P13599 (A23-S298)&P07151 (I21-M119) ≥ 95%, as determined by reducing SDS-PAGE.
HY-P75761 FCGRT-B2M Heterodimer Protein, Rat (Biotinylated, HEK293, His) P13599 (A23-S298)&P07151 (I21-M119) ≥ 85%, as determined by reducing SDS-PAGE.
HY-P78625 B2M/Beta-2 microglobulin Protein, Rat (HEK293, His) NP_036644 (I21-M119) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01299 B2M Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS16933 B2m Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23376 B2m Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens B2m NCBI NCBI:567