Gad2 - glutamate decarboxylase 2 Gene

Also Known as gad65

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 24380

Summary

Enables glutamate binding activity; glutamate decarboxylase activity; and pyridoxal phosphate binding activity. Involved in glutamate decarboxylation to succinate and response to xenobiotic stimulus. Located in several cellular components, including inhibitory synapse; perinuclear region of cytoplasm; and synaptic vesicle membrane. Is anchored component of membrane. Human ortholog(s) of this gene implicated in gestational diabetes; schizophrenia; and type 1 diabetes mellitus. Orthologous to human GAD2 (glutamate decarboxylase 2). [provided by Alliance of Genome Resources, Apr 2022]

Gad2 Products (1)

mRNA Protein Name
NM_012563.2 NP_036695.1 glutamate decarboxylase 2
Protein Preferred Names Protein Names

glutamate decarboxylase 2

  • 65 kDa glutamic acid decarboxylase

  • GAD-65

  • Glutamate decarboxylase 2 (islet)

  • glutamic acid decarboxylase 2

  • glutamic acid decarboxylase 65

Orthologs Information

Species Symbol Source ID
Homo sapiens Gad2 NCBI NCBI:2572