Gp6 - glycoprotein 6 (platelet) Gene

Also Known as Gpvi; Gm469; 9830166G18Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 243816

Summary

Enables Collagen binding activity and Collagen receptor activity. Involved in vasculature development. Acts upstream of or within collagen-activated tyrosine kinase receptor signaling pathway. Is integral component of plasma membrane. Is expressed in bone marrow; femur; liver; and spleen. Human ortholog(s) of this gene implicated in platelet-type bleeding disorder 11. Orthologous to human GP6 (Glycoprotein VI platelet). [provided by Alliance of Genome Resources, Apr 2022]

Gp6 Products (1)

mRNA Protein Name
NM_001163014.1 NP_001156486.1 platelet glycoprotein VI precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables collagen binding IDA
IDA: Inferred from direct assay
10961879 MGI
enables collagen receptor activity IMP
IMP: Inferred from mutant phenotype
27609517 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within collagen-activated signaling pathway IMP
IMP: Inferred from mutant phenotype
27609517 MGI
acts upstream of or within collagen-activated tyrosine kinase receptor signaling pathway IDA
IDA: Inferred from direct assay
28032533 MGI
acts upstream of or within collagen-activated tyrosine kinase receptor signaling pathway IMP
IMP: Inferred from mutant phenotype
27609517 MGI
acts upstream of or within peptidyl-tyrosine phosphorylation IDA
IDA: Inferred from direct assay
28032533 MGI
acts upstream of or within platelet aggregation IDA
IDA: Inferred from direct assay
28032533 MGI
Cellular Component GO Annotation Evidence References Source
located in cell surface IDA
IDA: Inferred from direct assay
28032533 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
10961879 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

platelet glycoprotein VI

  • glycoprotein 5

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05611 GP6 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17621 Gp6 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24081 Gp6 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gp6 NCBI NCBI:51206