Retn - resistin Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 246250

Summary

Predicted to enable hormone activity. Involved in several processes, including positive regulation of cell communication; positive regulation of smooth muscle cell migration; and positive regulation of smooth muscle cell proliferation. Located in extracellular space and nucleus. Used to study colitis. Biomarker of non-alcoholic fatty liver disease. Human ortholog(s) of this gene implicated in hypertension; hypertrophic cardiomyopathy; obesity; and type 2 diabetes mellitus. Orthologous to human RETN (resistin). [provided by Alliance of Genome Resources, Apr 2022]

Retn Products (1)

mRNA Protein Name
NM_144741.1 NP_653342.1 resistin precursor

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in fat cell differentiation IMP
IMP: Inferred from mutant phenotype
15191360 RGD
involved in negative regulation of feeding behavior IDA
IDA: Inferred from direct assay
19183337 RGD
involved in positive regulation of progesterone secretion IDA
IDA: Inferred from direct assay
21239528 RGD
involved in positive regulation of synaptic transmission IDA
IDA: Inferred from direct assay
22702339 RGD
involved in response to insulin IMP
IMP: Inferred from mutant phenotype
15191360 RGD
involved in response to mechanical stimulus IEP
IEP: Inferred from expression pattern
20310085 RGD
Cellular Component GO Annotation Evidence References Source
located in extracellular space IDA
IDA: Inferred from direct assay
16125524 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

resistin

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11857 RETN Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19945 Retn Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26447 Retn Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Retn NCBI NCBI:56729