Pgk1 - phosphoglycerate kinase 1 Gene

Also Known as Pgk

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 24644

Summary

Enables ADP binding activity; ATP binding activity; and phosphoglycerate kinase activity. Involved in gluconeogenesis and glycolytic process. Located in cytosol. Human ortholog(s) of this gene implicated in hemolytic anemia and phosphoglycerate kinase 1 deficiency. Orthologous to human PGK1 (phosphoglycerate kinase 1). [provided by Alliance of Genome Resources, Apr 2022]

Pgk1 Products (1)

mRNA Protein Name
NM_053291.3 NP_445743.2 phosphoglycerate kinase 1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables ADP binding IDA
IDA: Inferred from direct assay
6405813 RGD
enables ATP binding IMP
IMP: Inferred from mutant phenotype
3091090 RGD
enables phosphoglycerate kinase activity IDA
IDA: Inferred from direct assay
1834654 RGD
enables phosphoglycerate kinase activity IMP
IMP: Inferred from mutant phenotype
3091090 RGD
Biological Process GO Annotation Evidence References Source
involved in gluconeogenesis IDA
IDA: Inferred from direct assay
15720133 RGD
involved in gluconeogenesis IMP
IMP: Inferred from mutant phenotype
3091090 RGD
involved in glycolytic process IDA
IDA: Inferred from direct assay
6405813 RGD
involved in glycolytic process IMP
IMP: Inferred from mutant phenotype
3091090 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

phosphoglycerate kinase 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (6)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-W195984 Z57346765 99.85% Unkown
HY-178761 PGK1-IN-1 Inhibitor 99.78% Unkown
HY-N8540 Ilicicolin H Inhibitor 96.7% Unkown
HY-178989 PGK1-IN-2 Inhibitor / Unkown
HY-177944 DC-PGKI Inhibitor / Unkown
HY-184191 PGK1-IN-3 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pgk1 NCBI NCBI:5230