Tk1 - thymidine kinase 1 Gene

Also Known as Tk

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 24834

Summary

Enables identical protein binding activity. Involved in several processes, including fetal process involved in parturition; response to cortisol; and thymidine metabolic process. Predicted to be located in cytoplasm. Orthologous to human TK1 (thymidine kinase 1). [provided by Alliance of Genome Resources, Apr 2022]

Tk1 Products (1)

mRNA Protein Name
NM_052800.1 NP_434687.1 thymidine kinase, cytosolic

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables identical protein binding IPI
IPI: Inferred from physical interaction
23351158 RGD
Biological Process GO Annotation Evidence References Source
involved in digestive tract development IEP
IEP: Inferred from expression pattern
6701043 RGD
involved in fetal process involved in parturition IEP
IEP: Inferred from expression pattern
7208144 RGD
involved in liver development IEP
IEP: Inferred from expression pattern
995499 RGD
involved in response to copper ion IEP
IEP: Inferred from expression pattern
6642140 RGD
involved in response to cortisol IEP
IEP: Inferred from expression pattern
7208144 RGD
involved in response to nutrient levels IEP
IEP: Inferred from expression pattern
6701043 RGD
involved in response to toxic substance IEP
IEP: Inferred from expression pattern
6642140 RGD
involved in skeletal muscle cell proliferation IEP
IEP: Inferred from expression pattern
15748706 RGD
involved in thymidine metabolic process IDA
IDA: Inferred from direct assay
6642140 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

thymidine kinase, cytosolic

  • thymidine kinase 1, soluble

Tk1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
Tk1 P27158 Tk1 Rattus norvegicus P27158
GMS
23351158
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (9)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-W342664 2'-Deoxy-2'-fluoro-5-iodouridine 99.46% Unkown
HY-128710 2'-Fluorothymidine 99.07% Unkown
HY-104083 North-methanocarbathymidine Inhibitor / Unkown
HY-RS14556 TK1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W770090 CF 1743-d7 Inhibitor / Unkown
HY-107025 Cf1743 99.44% Unkown
HY-128710R 2'-Fluorothymidine (Standard) / Unkown
HY-RS17046 Tk1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23490 Tk1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tk1 NCBI NCBI:7083