Yes1 - YES proto-oncogene 1, Src family tyrosine kinase Gene

Also Known as Yes; c-Yes; p61-Yes; p60c-yes

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 24884

Summary

Enables epidermal growth factor receptor binding activity and protein tyrosine kinase activity. Involved in protein autophosphorylation. Located in plasma membrane. Is active in glutamatergic synapse and postsynaptic specialization, intracellular component. Orthologous to human YES1 (Yes proto-oncogene 1, Src family tyrosine kinase). [provided by Alliance of Genome Resources, Apr 2022]

Yes1 Products (3)

mRNA Protein Name
NM_001398584.1 NP_001385513.1 tyrosine-protein kinase Yes isoform 1
NM_001398585.1 NP_001385514.1 tyrosine-protein kinase Yes isoform 1
NM_033298.2 NP_150640.1 tyrosine-protein kinase Yes isoform 2
Protein Preferred Names Protein Names

tyrosine-protein kinase Yes

  • Yamagichi sarcoma viral (v-yes-1) oncogene homolog 1

  • Yamaguchi sarcoma viral (v-yes) oncogene homolog 1

  • Yamaguchi sarcoma viral oncogene homolog 1

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-112096 eCF506 Inhibitor 99.77% Phase 1

Pre-clinical Phase

Bioactive Molecules (13)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-135299 CH6953755 Inhibitor 99.75% Unkown
HY-136848 SM1-71 Inhibitor 96.09% Unkown
HY-137342 SB1-G-187 Degrader 98.70% Unkown
HY-137343 DB-0646 Degrader 98.0% Unkown
HY-RS15922 YES1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-145373 BMS-986143 Inhibitor / Unkown
HY-112096S eCF506-d5 Inhibitor / Unkown
HY-184792 CA/PRAK-IN-1 Inhibitor / Unkown
HY-E70293 N-Acetylgalactosaminyltransferase 12 / Unkown
HY-174505 Human YAP1 mRNA / Unkown
HY-208739 SRC tyrosine kinase IN-1 Inhibitor / Unkown
HY-RS16970 Yes1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23413 Yes1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Yes1 NCBI NCBI:7525