Stx1b - syntaxin 1B Gene

Also Known as Stx2; Stx1b2

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 24923

Summary

Enables protein domain specific binding activity and signaling receptor binding activity. Involved in exocytic insertion of neurotransmitter receptor to postsynaptic membrane and regulation of exocytosis. Located in presynaptic active zone membrane. Human ortholog(s) of this gene implicated in generalized epilepsy with febrile seizures plus 9. Orthologous to human STX1B (syntaxin 1B). [provided by Alliance of Genome Resources, Apr 2022]

Stx1b Products (1)

mRNA Protein Name
NM_012700.2 NP_036832.1 syntaxin-1B

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
12093152 RGD
enables protein domain specific binding IPI
IPI: Inferred from physical interaction
8999968 RGD
enables signaling receptor binding IPI
IPI: Inferred from physical interaction
21424589 RGD
Biological Process GO Annotation Evidence References Source
involved in protein localization to membrane IDA
IDA: Inferred from direct assay
12093152 RGD
involved in regulation of exocytosis IMP
IMP: Inferred from mutant phenotype
11245593 RGD
involved in vesicle-mediated transport IMP
IMP: Inferred from mutant phenotype
11245593 RGD
Cellular Component GO Annotation Evidence References Source
located in presynaptic membrane IDA
IDA: Inferred from direct assay
12093152 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

syntaxin-1B

  • P35B

  • Syntaxin 2

  • syntaxin 1B2

Stx1b Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
Stx1b P61265 Rnf40 Rattus norvegicus Q8CJB9
Y2H
12121982
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13981 STX1B Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Stx1b NCBI NCBI:112755