Tacr2 - tachykinin receptor 2 Gene

Rattus norvegicus

Also known as Tac2r

Gene ID: 25007 | Gene type: protein coding

About Tacr2

Primary_assembly 20: 30,208,907-30,223,446 forward strand.mRatBN7.2:CM026993.1

This gene has 1 transcript (splice variant), 200 orthologues, 50 paralogues and is associated with 6 phenotypes. Biased expression in Adrenal (RPKM 43.), Uterus (RPKM 5.5) and 1 other tissue.

Summary

Enables substance K receptor activity. Involved in several processes, including operant conditioning; positive regulation of uterine smooth muscle contraction; and regulation of secretion by cell. Located in membrane. Used to study colitis and pulmonary hypertension. Biomarker of colitis. Human ortholog(s) of this gene implicated in asthma. Orthologous to human TACR2 (tachykinin receptor 2). [provided by Alliance of Genome Resources, Apr 2022]

Tacr2 Products(1)

mRNA	Protein	Name
NM_080768.1	NP_542946.1	substance-K receptor

Tacr2 Protein Structure

7tmA_SKR_NK2R

0
100
200
300
390 a.a.

Protein Preferred Names

Protein Names

substance-K receptor

NK-2 receptor	NK-2R
SKR	Tachykinin 2 (substance K) receptor
neurokinin A receptor

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Purity	Rare Diseases
HY-RS14146	TACR2 Human Pre-designed siRNA Set A	/	Unkown
HY-RS14147	Tacr2 Mouse Pre-designed siRNA Set A	/	Unkown
HY-RS14148	Tacr2 Rat Pre-designed siRNA Set A	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Tacr2	NCBI	NCBI:6865

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