Arnt - aryl hydrocarbon receptor nuclear translocator Gene

Also Known as Arnt1

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 25242

Summary

Contributes to sequence-specific DNA binding activity. Involved in response to dexamethasone and response to hypoxia. Located in nucleus. Human ortholog(s) of this gene implicated in renal cell carcinoma. Orthologous to human ARNT (Aryl Hydrocarbon Receptor nuclear translocator). [provided by Alliance of Genome Resources, Apr 2022]

Arnt Products (2)

mRNA Protein Name
NM_001389231.2 NP_001376160.2 aryl hydrocarbon receptor nuclear translocator isoform 2
NM_012780.3 NP_036912.3 aryl hydrocarbon receptor nuclear translocator isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
11259609 RGD
enables protein-containing complex binding IDA
IDA: Inferred from direct assay
11029639 RGD
contributes to sequence-specific DNA binding IDA
IDA: Inferred from direct assay
11029639 RGD
Biological Process GO Annotation Evidence References Source
involved in G1 to G0 transition IMP
IMP: Inferred from mutant phenotype
15492120 RGD
involved in circadian rhythm IEP
IEP: Inferred from expression pattern
9813174 RGD
involved in nitric oxide metabolic process IEP
IEP: Inferred from expression pattern
31489946 RGD
involved in response to dexamethasone IEP
IEP: Inferred from expression pattern
27856527 RGD
involved in response to hypoxia IEP
IEP: Inferred from expression pattern
10873592 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

aryl hydrocarbon receptor nuclear translocator

  • Aryl hydrocarbon receptor nuclear translocator 1

  • HIF-1-beta

  • HIF1-beta

  • dioxin receptor, nuclear translocator

  • hypoxia-inducible factor 1-beta

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Phase
HY-16031A AFP464 / Phase 2
HY-183117 NEO-811 Degrader / Phase 1

Pre-clinical Phase

Bioactive Molecules (14)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-120087 KG-548 Inhibitor 99.90% Unkown
HY-D0932 Sudan IV 98.0% Unkown
HY-19621 THS-044 Modulator 99.67% Unkown
HY-159644 Casdatifan 96.37% Unkown
HY-112374 NPAS3-IN-1 Inhibitor 98.72% Unkown
HY-RS01011 ARNT Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W012248 KG-655 Inhibitor 99.87% Unkown
HY-183583 HIF-2α-IN-18 Inhibitor / Unkown
HY-186020 L-4-Aminoarabinose-bactoprenyl phosphate / Unkown
HY-RS01012 ARNT2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS08421 MIA3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-D0932S Sudan IV-d6 / Unkown
HY-RS18908 Arnt Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25399 Arnt Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Arnt NCBI NCBI:405