Id1 - inhibitor of DNA binding 1 Gene

Also Known as Idb1; ID125A

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 25261

Summary

Enables several functions, including identical protein binding activity; Proteasome binding activity; and protein C-terminus binding activity. Involved in several processes, including cellular response to growth factor stimulus; cellular response to organonitrogen compound; and nervous system development. Located in centrosome and nucleus. Used to study pulmonary hypertension. Biomarker of cholestasis. Orthologous to human ID1 (inhibitor of DNA binding 1, HLH protein). [provided by Alliance of Genome Resources, Apr 2022]

Id1 Products (2)

mRNA Protein Name
NM_012797.2 NP_036929.2 DNA-binding protein inhibitor ID-1
NM_012797.2 NP_036929.2 DNA-binding protein inhibitor ID-1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables identical protein binding IPI
IPI: Inferred from physical interaction
8106493 RGD
enables proteasome binding IPI
IPI: Inferred from physical interaction
23831032 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
19167333 RGD
Biological Process GO Annotation Evidence References Source
involved in cell-abiotic substrate adhesion IEP
IEP: Inferred from expression pattern
11600477 RGD
involved in cellular response to dopamine IEP
IEP: Inferred from expression pattern
20600660 RGD
involved in cellular response to epidermal growth factor stimulus IEP
IEP: Inferred from expression pattern
7623812 RGD
involved in cellular response to nerve growth factor stimulus IEP
IEP: Inferred from expression pattern
7623812 RGD
involved in cellular response to peptide IEP
IEP: Inferred from expression pattern
16706836 RGD
involved in cellular response to transforming growth factor beta stimulus IEP
IEP: Inferred from expression pattern
16628634 RGD
involved in negative regulation of apoptotic process IMP
IMP: Inferred from mutant phenotype
19137015 RGD
involved in negative regulation of dendrite morphogenesis IMP
IMP: Inferred from mutant phenotype
19167333 RGD
involved in negative regulation of endothelial cell differentiation IMP
IMP: Inferred from mutant phenotype
20830586 RGD
involved in negative regulation of transcription by RNA polymerase II IMP
IMP: Inferred from mutant phenotype
23831032 RGD
involved in neuron differentiation IEP
IEP: Inferred from expression pattern
7908517 RGD
involved in positive regulation of actin filament bundle assembly IMP
IMP: Inferred from mutant phenotype
16628634 RGD
involved in positive regulation of epithelial cell proliferation IMP
IMP: Inferred from mutant phenotype
23335245 RGD
involved in positive regulation of gene expression IMP
IMP: Inferred from mutant phenotype
23335245 RGD
involved in regulation of vasculature development IMP
IMP: Inferred from mutant phenotype
21472453 RGD
involved in response to organic cyclic compound IEP
IEP: Inferred from expression pattern
20600660 RGD
Cellular Component GO Annotation Evidence References Source
located in centrosome IDA
IDA: Inferred from direct assay
19167333 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

DNA-binding protein inhibitor ID-1

  • Inhibitor of DNA binding 1 helix-loop-helix protein (splice varaiation)

  • Inhibitor of DNA binding 1, helix-loop-helix protein (splice variation)

  • inhibitor of DNA binding 1, HLH protein

  • inhibitor of DNA binding 1, dominant negative helix-loop-helix prote

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (10)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-124697 BMP signaling agonist sb4 Agonist 99.98% Unkown
HY-129241 AGX51 Antagonist 99.33% Unkown
HY-80012 SJB3-019A Inhibitor 99.88% Unkown
HY-110245 DMH2 Inducer 99.84% Unkown
HY-RS06522 ID1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS06528 Idh1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-N20711 Usenamine A / Unkown
HY-114802 O-1663 / Unkown
HY-RS16689 Id1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23124 Id1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Id1 NCBI NCBI:3397