Cdk11b - cyclin-dependent kinase 11B Gene

Also Known as Cdk11; Cdc2l1

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 252879

About Cdk11b

Primary_assembly 5: 166,212,829-166,238,876 forward strand.mRatBN7.2:CM026978.1

This gene has 2 transcripts (splice variants), 203 orthologues, 24 paralogues and is associated with 13 phenotypes. Biased expression in Thymus (RPKM 8.7), Spleen (RPKM 77.3) and 9 other tissues.

Summary

Predicted to enable ATP binding activity and cyclin-dependent protein serine/threonine kinase activity. Predicted to be involved in several processes, including protein phosphorylation; regulation of cell growth; and regulation of mRNA processing. Predicted to act upstream of or within blastocyst development; negative regulation of apoptotic signaling pathway; and regulation of mitotic nuclear division. Predicted to be located in nuclear membrane and perinuclear region of cytoplasm. Predicted to be active in nucleus. Orthologous to several human genes including CDK11B (cyclin dependent kinase 11B). [provided by Alliance of Genome Resources, Apr 2022]

Cdk11b Products (1)

mRNA Protein Name
NM_145766.2 NP_665709.2 cyclin-dependent kinase 11B

Cdk11b Protein Structure

STKc_CDC2L1

STKc_CDC2L1: cd07843 (420 - 711)

  • 0
  • 200
  • 400
  • 600
  • 784 a.a.
Protein Preferred Names Protein Names

cyclin-dependent kinase 11B

  • PITSLRE serine/threonine-protein kinase CDC2L1

  • cell division cycle 2 homolog-like 1

  • cell division cycle 2-like protein kinase 1

  • cell division protein kinase 11

  • cyclin-dependent kinase 11

  • galactosyltransferase-associated protein kinase p58/GTA

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (9)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-12467 OTS964 hydrochloride 99.74% Unkown
HY-155874 ZNL-05-044 Inhibitor 99.11% Unkown
HY-148061 DB1113 99.86% Unkown
HY-148063 DB0614 99.92% Unkown
HY-148066 DB0662 Degrader 99.66% Unkown
HY-19718 OTS964 / Unkown
HY-RS02353 CDK11B Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS02354 Cdk11b Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS02355 Cdk11b Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cdk11b NCBI NCBI:984