Ahsg - alpha-2-HS-glycoprotein Gene

Also Known as pp63; Aa2-066

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 25373

Summary

Enables receptor signaling protein tyrosine kinase inhibitor activity. Involved in several processes, including animal organ development; negative regulation of bone mineralization; and positive regulation of bone resorption. Located in collagen-containing extracellular matrix and extracellular space. Part of protein-containing complex. Human ortholog(s) of this gene implicated in alopecia-mental retardation syndrome 1; coronary artery disease; and type 2 diabetes mellitus. Orthologous to human AHSG (alpha 2-HS glycoprotein). [provided by Alliance of Genome Resources, Apr 2022]

Ahsg Products (1)

mRNA Protein Name
NM_012898.5 NP_037030.2 alpha-2-HS-glycoprotein precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables receptor signaling protein tyrosine kinase inhibitor activity IDA
IDA: Inferred from direct assay
2766355 RGD
Biological Process GO Annotation Evidence References Source
involved in animal organ regeneration IEP
IEP: Inferred from expression pattern
1659407 RGD
involved in cellular response to insulin stimulus IEP
IEP: Inferred from expression pattern
7513166 RGD
involved in cerebral cortex development IEP
IEP: Inferred from expression pattern
2423927 RGD
involved in male gonad development IMP
IMP: Inferred from mutant phenotype
6530227 RGD
involved in negative regulation of bone mineralization IMP
IMP: Inferred from mutant phenotype
8702833 RGD
involved in negative regulation of cell growth IDA
IDA: Inferred from direct assay
2766355 RGD
involved in negative regulation of insulin receptor signaling pathway IDA
IDA: Inferred from direct assay
2766355 RGD
involved in positive regulation of bone resorption IMP
IMP: Inferred from mutant phenotype
10500999 RGD
involved in protein-containing complex assembly IPI
IPI: Inferred from physical interaction
12676928 RGD
Cellular Component GO Annotation Evidence References Source
located in collagen-containing extracellular matrix IDA
IDA: Inferred from direct assay
7794128 RGD
located in extracellular space IDA
IDA: Inferred from direct assay
11239198 RGD
part of protein-containing complex IDA
IDA: Inferred from direct assay
12676928 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

alpha-2-HS-glycoprotein

  • 59 kDa bone sialic acid-containing protein

  • BSP

  • alpha 2 HS-glycoprotein alpha 2 (fetuin)

  • fetuin-A

  • glycoprotein PP63

  • phosphorylated N-glycoprotein pp63

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS00486 AHSG Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18226 Ahsg Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24703 Ahsg Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ahsg NCBI NCBI:197