Mak - male germ cell-associated kinase Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 25677

Summary

Predicted to enable protein serine/threonine kinase activity and transcription coactivator activity. Predicted to be involved in several processes, including cilium organization; photoreceptor cell maintenance; and protein autophosphorylation. Predicted to act upstream of or within negative regulation of non-motile cilium assembly. Predicted to be located in several cellular components, including ciliary tip; cytoskeleton; and photoreceptor cell cilium. Predicted to be active in cilium; cytoplasm; and nucleus. Human ortholog(s) of this gene implicated in retinitis pigmentosa 62. Orthologous to human MAK (male germ cell associated kinase). [provided by Alliance of Genome Resources, Apr 2022]

Mak Products (1)

mRNA Protein Name
NM_013136.3 NP_037268.2 serine/threonine-protein kinase MAK
Protein Preferred Names Protein Names

serine/threonine-protein kinase MAK

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-103663 MAK683 Inhibitor 99.02% Phase 2

Pre-clinical Phase

Bioactive Molecules (8)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-130815A MAK683-C2-acid hydrochloride Inhibitor 99.60% Unkown
HY-130815 MAK683-CH2CH2COOH Inhibitor / Unkown
HY-103663A MAK683 hydrochloride Inhibitor / Unkown
HY-RS00631 ALPK3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS07989 MAK Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS07990 MAK16 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17873 Mak Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24342 Mak Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Bioactive MoleculesInhibitory Antibodies (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P99425 Afelimomab 99.34% Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mak NCBI NCBI:4117