Avpr1b - arginine vasopressin receptor 1B Gene

Also Known as VIBR; VPR3; AVPR3; V3/V1b

Species: Mus musculus

Gene Type: protein coding
Gene ID: 26361

About Avpr1b

Chromosome 1: 131,526,977-131,539,738 forward strand.GRCm39:CM000994.3

This gene has 2 transcripts (splice variants), 132 orthologues, 16 paralogues and is associated with 7 phenotypes. Low expression observed in reference dataset.

Summary

Predicted to enable peptide binding activity and Vasopressin Receptor activity. Involved in multicellular organism aging and regulation of blood pressure. Acts upstream of or within regulation of systemic arterial blood pressure by vasopressin. Predicted to be located in Golgi apparatus and plasma membrane. Predicted to be integral component of plasma membrane. Is expressed in several structures, including alimentary system; brain; eye; genitourinary system; and immune system. Human ortholog(s) of this gene implicated in autism spectrum disorder; bipolar disorder; and mood disorder. Orthologous to human AVPR1B (arginine Vasopressin Receptor 1B). [provided by Alliance of Genome Resources, Apr 2022]

Avpr1b Products (1)

mRNA Protein Name
NM_011924.2 NP_036054.1 vasopressin V1b receptor

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in regulation of blood pressure IMP
IMP: Inferred from mutant phenotype
26531127 MGI
acts upstream of or within regulation of systemic arterial blood pressure by vasopressin IGI
IGI: Inferred from genetic interaction
12486173 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Avpr1b Protein Structure

7tmA_V1bR

7tmA_V1bR: cd15386 (34 - 345)

7tmA_V1bR

7tmA_V1bR: cd15386 (35 - 61)

7tmA_V1bR

7tmA_V1bR: cd15386 (68 - 95)

7tmA_V1bR

7tmA_V1bR: cd15386 (106 - 136)

7tmA_V1bR

7tmA_V1bR: cd15386 (148 - 169)

7tmA_V1bR

7tmA_V1bR: cd15386 (195 - 224)

7tmA_V1bR

7tmA_V1bR: cd15386 (270 - 300)

7tmA_V1bR

7tmA_V1bR: cd15386 (313 - 338)

DUF1856

DUF1856: pfam08983 (358 - 407)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 421 a.a.
Protein Preferred Names Protein Names

vasopressin V1b receptor

  • AVPR V1b

  • AVPR V3

  • V3/V1b pituitary vasopressin receptor

  • antidiuretic hormone receptor 1b

  • arginine vasopressin type 1b receptor

  • vasopressin V3 receptor

Related Agents

  • Approval
  • Pre-clinical Phase

Approval

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P0049A Argipressin diacetate / Unkown

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01284 AVPR1B Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS01285 Avpr1b Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS01286 Avpr1b Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Avpr1b NCBI NCBI:553