Btd - biotinidase Gene

Species: Mus musculus

Gene Type: protein coding
Gene ID: 26363

Summary

Enables biotinidase activity. Acts upstream of or within biotin metabolic process. Located in apical part of cell; nucleolus; and perikaryon. Is expressed in blood vessel; inner ear; nervous system; and urinary system. Used to study biotinidase deficiency. Human ortholog(s) of this gene implicated in biotinidase deficiency. Orthologous to human BTD (biotinidase). [provided by Alliance of Genome Resources, Apr 2022]

Btd Products (2)

mRNA Protein Name
NM_001374217.1 NP_001361146.1 biotinidase isoform 2
NM_025295.4 NP_079571.1 biotinidase isoform 1 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables biotinidase activity IMP
IMP: Inferred from mutant phenotype
21051254 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within biotin metabolic process IMP
IMP: Inferred from mutant phenotype
21051254 MGI
involved in biotin metabolic process IMP
IMP: Inferred from mutant phenotype
24075304 MGI
Cellular Component GO Annotation Evidence References Source
located in apical part of cell IDA
IDA: Inferred from direct assay
16107307 MGI
is active in extracellular region IDA
IDA: Inferred from direct assay
21051254 MGI
located in nucleolus IDA
IDA: Inferred from direct assay
16107307 MGI
located in perikaryon IDA
IDA: Inferred from direct assay
16107307 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

biotinidase

  • biotinase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (10)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-128205 BTD Inhibitor 99.81% Unkown
HY-D2344 3-BTD 99.49% Unkown
HY-D2186 BTD probe-1 98.06% Unkown
HY-149975 AMPA receptor modulator-4 Activator / Unkown
HY-RS01659 BTD Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS13611 SP8 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W770437 Benzotriazole BT-d10 / Unkown
HY-D2371 3-BTMD / Unkown
HY-RS20234 Btd Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26741 Btd Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Btd NCBI NCBI:686