Gpr3 - G protein-coupled receptor 3 Gene

Also Known as Gpcr3

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 266769

Summary

Predicted to enable G protein-coupled receptor activity. Involved in positive regulation of cAMP-mediated signaling and regulation of cytosolic calcium ion concentration. Predicted to be located in nuclear membrane. Predicted to be active in cytoplasm and plasma membrane. Orthologous to human GPR3 (G protein-coupled receptor 3). [provided by Alliance of Genome Resources, Apr 2022]

Gpr3 Products (1)

mRNA Protein Name
NM_153727.2 NP_714949.2 G-protein coupled receptor 3

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in positive regulation of cAMP/PKA signal transduction IDA
IDA: Inferred from direct assay
12220620 RGD
involved in regulation of cytosolic calcium ion concentration IDA
IDA: Inferred from direct assay
12220620 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

G-protein coupled receptor 3

  • G protein-coupled receptor R4

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-108496 Sphingosine-1-phosphate Agonist 99.94% Phase 1

Pre-clinical Phase

Bioactive Molecules (8)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-12664 AF64394 Inhibitor 98.02% Unkown
HY-155318A GPR3 agonist-2 Agonist 99.90% Unkown
HY-108496S Sphingosine-1-phosphate-d7 Agonist 99.9% Unkown
HY-182011 GPR6 inverse agonist 2 Agonist / Unkown
HY-183657A GPR3 inverse agonist-1 TFA / Unkown
HY-RS05700 GPR3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17955 Gpr3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24426 Gpr3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gpr3 NCBI NCBI:2827