Pla2g2e - phospholipase A2, group IIE Gene

Species: Mus musculus

Gene Type: protein coding
Gene ID: 26970

Summary

Enables calcium-dependent Phospholipase A2 activity. Involved in phosphatidylcholine metabolic process and phosphatidylglycerol metabolic process. Acts upstream of or within low-density lipoprotein particle remodeling. Located in extracellular region. Is expressed in several structures, including alimentary system; cranium; heart; respiratory system; and telencephalon. Orthologous to human PLA2G2E (Phospholipase A2 group IIE). [provided by Alliance of Genome Resources, Apr 2022]

Pla2g2e Products (1)

mRNA Protein Name
NM_012044.2 NP_036174.1 group IIE secretory phospholipase A2 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables calcium-dependent phospholipase A2 activity IDA
IDA: Inferred from direct assay
10531313 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within low-density lipoprotein particle remodeling IMP
IMP: Inferred from mutant phenotype
24910243 MGI
involved in phosphatidylcholine metabolic process IDA
IDA: Inferred from direct assay
10531313 MGI
involved in phosphatidylglycerol metabolic process IDA
IDA: Inferred from direct assay
10531313 MGI
Cellular Component GO Annotation Evidence References Source
located in extracellular region IDA
IDA: Inferred from direct assay
10531313 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

group IIE secretory phospholipase A2

  • GIIE sPLA2

  • mGIIEsPLA2s

  • phosphatidylcholine 2-acylhydrolase 2E

  • sPLA2-IIE

Recombinant Pla2g2e Proteins

Cat. No. Product Name Accession Purity
HY-P77138 PLA2G2E Protein, Mouse (HEK293, His) Q9QUL3 (N20-C142) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS10623 PLA2G2E Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18318 Pla2g2e Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24796 Pla2g2e Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pla2g2e NCBI NCBI:30814