Taf1 - TATA-box binding protein associated factor 1 Gene

Also Known as Ccg1; KAT4; p250; Ccg-1; Taf2a; N-TAF1; TAFII250; B430306D02Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 270627

Summary

Enables DNA binding activity; Histone Acetyltransferase activity; and promoter-specific chromatin binding activity. Involved in histone acetylation. Located in pronucleus. Is expressed in several structures, including branchial arch; central nervous system; genitourinary system; hemolymphoid system gland; and sensory organ. Human ortholog(s) of this gene implicated in X-linked dystonia-parkinsonism and syndromic X-linked intellectual disability. Orthologous to several human genes including TAF1 (TATA-box binding protein associated factor 1). [provided by Alliance of Genome Resources, Apr 2022]

Taf1 Products (5)

mRNA Protein Name
NM_001290729.2 NP_001277658.1 transcription initiation factor TFIID subunit 1 isoform 1
NM_001405959.1 NP_001392888.1 transcription initiation factor TFIID subunit 1 isoform 2
NM_001405960.1 NP_001392889.1 transcription initiation factor TFIID subunit 1 isoform 3
NM_001405961.1 NP_001392890.1 transcription initiation factor TFIID subunit 1 isoform 4
NM_001405962.1 NP_001392891.1 transcription initiation factor TFIID subunit 1 isoform 5

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Références Source
enables DNA binding IDA
IDA: Inferred from direct assay
18722179 MGI
enables histone acetyltransferase activity IDA
IDA: Inferred from direct assay
11592977 MGI
enables promoter-specific chromatin binding IDA
IDA: Inferred from direct assay
22323595 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
11592977 MGI
Cellular Component GO Annotation Evidence Références Source
located in pronucleus IDA
IDA: Inferred from direct assay
16822332 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

transcription initiation factor TFIID subunit 1

  • TBP-associated factor 250 kDa

  • cell cycle gene 1 protein

  • cell cycle, G1 phase defect

  • transcription initiation factor TFIID 250 kDa subunit

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (23)
Cat. No. Nom du produit
Effect
Pureté
Rare Diseases
HY-107424 BAY-299 Inhibitor 99.40% Unkown
HY-112803 GNE-371 98.06% Unkown
HY-101088 CeMMEC13 Inhibitor 98.0% Unkown
HY-117997 UMB-32 Inhibitor 99.11% Unkown
HY-111445 CeMMEC1 Inhibitor 98.94% Unkown
HY-78197 3,5-Dimethylisoxazole-4-boronic acid pinacol ester 99.07% Unkown
HY-123621 GNE-375 Inhibitor 99.93% Unkown
HY-176457 ZS3-046 / Unkown
HY-150239 BAY-364 Inhibitor / Unkown
HY-176467 TAF1 ligand 1 Ligand / Unkown
HY-RS14157 TAF1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS14163 TAF1A Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS14164 TAF1C Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS14165 TAF1D Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS14166 TAF1L Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-111445A CeMMEC1 hydrochloride Inhibitor / Unkown
HY-RS16492 TAF1B Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17005 Taf1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22842 Taf1b Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22843 Taf1d Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23448 Taf1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29357 Taf1b Rat Pre-designed siRNA Set A / Unkown
HY-RS29358 Taf1d Rat Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Taf1 NCBI NCBI:6872