Hbp1 - HMG-box transcription factor 1 Gene

Also Known as Hmgb1

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 27080

Summary

Enables DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in negative regulation of transcription by RNA polymerase II and positive regulation of potassium ion transport. Predicted to be located in nuclear speck. Predicted to be active in nucleus. Orthologous to human HBP1 (HMG-box transcription factor 1). [provided by Alliance of Genome Resources, Apr 2022]

Hbp1 Products (1)

mRNA Protein Name
NM_013221.2 NP_037353.2 HMG box-containing protein 1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables DNA-binding transcription repressor activity, RNA polymerase II-specific IDA
IDA: Inferred from direct assay
15024088 RGD
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: Inferred from direct assay
15024088 RGD
Biological Process GO Annotation Evidence References Source
involved in negative regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
15024088 RGD
involved in positive regulation of potassium ion transport IDA
IDA: Inferred from direct assay
7937077 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

HMG box-containing protein 1

  • high mobility group box transcription factor 1

  • high mobility group protein 1

Related Agents

  • Approval
  • Pre-clinical Phase

Approval

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-B1165 Cyproheptadine (hydrochloride sesquihydrate) 99.74% Unkown

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06033 HBP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18616 Hbp1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25102 Hbp1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Hbp1 NCBI NCBI:26959