Rab5a - RAB5A, member RAS oncogene family Gene

Also Known as nnyRab5a; 2410015H04Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 271457

Summary

Enables GTPase activity and guanyl nucleotide binding activity. Acts upstream of or within endocytosis. Located in several cellular components, including cytoplasmic vesicle; membrane raft; and ruffle. Is expressed in several structures, including brain; cardiovascular system; eye; genitourinary system; and gut. Orthologous to human RAB5A (RAB5A, member Ras oncogene family). [provided by Alliance of Genome Resources, Apr 2022]

Rab5a Products (1)

mRNA Protein Name
NM_025887.4 NP_080163.1 ras-related protein Rab-5A

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables GTPase activity IDA
IDA: Inferred from direct assay
12446704 MGI
enables guanyl nucleotide binding IDA
IDA: Inferred from direct assay
12446704 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
20534488 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within endocytosis IDA
IDA: Inferred from direct assay
8197185 MGI
Cellular Component GO Annotation Evidence References Source
located in actin cytoskeleton IDA
IDA: Inferred from direct assay
21419809 MGI
located in cytoplasm IDA
IDA: Inferred from direct assay
18656450 MGI
located in early endosome IDA
IDA: Inferred from direct assay
8197185 MGI
located in early phagosome IDA
IDA: Inferred from direct assay
25568335 MGI
located in endocytic vesicle IDA
IDA: Inferred from direct assay
8197185 MGI
located in endosome IDA
IDA: Inferred from direct assay
18794329 MGI
located in membrane raft IDA
IDA: Inferred from direct assay
12388596 MGI
located in phagocytic vesicle IDA
IDA: Inferred from direct assay
22493499 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
8197185 MGI
located in ruffle IDA
IDA: Inferred from direct assay
12446704 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ras-related protein Rab-5A

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11571 RAB5A Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21715 Rab5a Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28233 Rab5a Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rab5a NCBI NCBI:5868