PRLHR - prolactin releasing hormone receptor Gene

Also Known as GR3; GPR10; PrRPR

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 2834

About PRLHR

Cytogenetic location: 10q26.11 Genomic coordinates (GRCh38): 10:118,589,997-118,595,648 (from NCBI)

This gene has 2 transcripts (splice variants), 179 orthologues and 33 paralogues. Biased expression in adrenal (RPKM 3.6), endometrium (RPKM 1.7) and 1 other tissue.

Summary

PRLHR is a 7-transmembrane domain receptor for prolactin-releasing hormone (PRLH; MIM 602663) that is highly expressed in anterior pituitary (Ozawa et al., 2002 [PubMed 11923475]).[supplied by OMIM, Mar 2008]

PRLHR Products (1)

mRNA Protein Name
NM_004248.3 NP_004239.2 prolactin-releasing peptide receptor

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
11641419 GOA
Cellular Component GO Annotation Evidence References Source
located in cilium IDA
IDA: Inferred from direct assay
28154160 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

PRLHR Protein Structure

7tm_1

7tm_1: 7 transmembrane receptor (rhodopsin family) (77 - 335)

  • 0
  • 100
  • 200
  • 300
  • 370 a.a.
Protein Preferred Names Protein Names

prolactin-releasing peptide receptor

  • G-protein coupled receptor 10

PRLHR Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
PRLHR P49683 GRIP1 Homo sapiens Q9Y3R0
Anti Tag CoIP
11641419
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Body Mass Index Quantitative Trait Locus 11

  • OBESITY

  • Obesity, Susceptibility To

  • Leanness, Inherited

  • Obesity, Susceptibility To, Bmiq11

  • Obesity, Mild, Early-Onset

  • Obesity, Association With

  • Obesity, Early-Onset, Susceptibility To

  • Obesity, Severe

  • Obesity, Severe, And Type Ii Diabetes

  • Obesity, Late-Onset

  • Obesity , Susceptibility To

  • BMIQ11

  • Obesity Bmiq11

  • Obesity, Early-Onset

  • Simple Obesity Nos

  • Excess Fat

  • Obesity, Not Elsewhere Classified, Body Mass Index Not Elsewhere Classified

  • Adiposis
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11162 PRLHR Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21698 Prlhr Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28216 Prlhr Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus PRLHR VGNC VGNC:33345
Canis familiaris PRLHR VGNC VGNC:44993
Rattus norvegicus PRLHR RGD RGD:71037
Mus musculus PRLHR MGD MGI:2135956