VSTM1 - V-set and transmembrane domain containing 1 Gene

Also Known as SIRL1; SIRL-1; UNQ3033

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 284415

About VSTM1

Cytogenetic location: 19q13.42 Genomic coordinates (GRCh38): 19:54,040,825-54,063,897 (from NCBI)

This gene has 7 transcripts (splice variants), 1 gene allele, 199 orthologues and 25 paralogues. Restricted expression toward bone marrow (RPKM 28.7).

Summary

Predicted to enable cytokine activity. Predicted to be involved in immune system process and signal transduction. Predicted to be located in extracellular space. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]

VSTM1 Products (4)

mRNA Protein Name
NM_001288791.2 NP_001275720.1 V-set and transmembrane domain-containing protein 1 isoform 2
NM_001288792.2 NP_001275721.1 V-set and transmembrane domain-containing protein 1 isoform 3 precursor
NM_001288793.2 NP_001275722.1 V-set and transmembrane domain-containing protein 1 isoform 4
NM_198481.4 NP_940883.2 V-set and transmembrane domain-containing protein 1 isoform 1 precursor

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence Verweise Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

VSTM1 Protein Structure

Ig_2

Ig_2: Immunoglobulin domain (29 - 117)

  • 0
  • 100
  • 200
  • 236 a.a.
Protein Preferred Names Protein Names

V-set and transmembrane domain-containing protein 1

  • LAIR homolog

Recombinant VSTM1 Proteins

Art. -Nr. Produktname Accession Reinheit
HY-P71428 VSTM1 Protein, Human (119a.a, HEK293, His) Q6UX27 (Y17-T135) ≥ 95%, as determined by reducing SDS-PAGE.
HY-P77282 VSTM1 Protein, Human (HEK293, Fc) Q6UX27 (Y17-T135) ≥ 90%, as determined by reducing SDS-PAGE.

Related Diseases

Diseases Alias
Hypothyroidism, Central, With Testicular Enlargement

  • X-Linked Central Congenital Hypothyroidism With Late-Onset Testicular Enlargement

  • CHTE

  • Hypothyroidism, Central, And Testicular Enlargement

  • Igsf1 Deficiency Syndrome

  • X-Linked Central Congenital Hypothyroidism With Late-Onset Macroorchidism

  • Central Hypothyroidism And Testicular Enlargement

  • Hypothyroidism, Central, Testicular Enlargement
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-RS15713 VSTM1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20518 Vstm1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27027 Vstm1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris VSTM1 VGNC VGNC:54001
Bos taurus VSTM1 VGNC VGNC:57056
Rattus norvegicus VSTM1 RGD RGD:2322891
Others VSTM1 NCBI