VSTM1 - V-set and transmembrane domain containing 1 Gene

Homo sapiens

Also known as SIRL1; SIRL-1; UNQ3033

Gene ID: 284415 | Gene type: protein coding

About VSTM1

Cytogenetic location: 19q13.42 Genomic coordinates (GRCh38): 19:54,040,825-54,063,897 (from NCBI)

This gene has 7 transcripts (splice variants), 1 gene allele, 199 orthologues and 25 paralogues. Restricted expression toward bone marrow (RPKM 28.7).

Summary

Predicted to enable cytokine activity. Predicted to be involved in immune system process and signal transduction. Predicted to be located in extracellular space. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]

VSTM1 Products(4)

mRNA	Protein	Name
NM_001288791.2	NP_001275720.1	V-set and transmembrane domain-containing protein 1 isoform 2
NM_001288792.2	NP_001275721.1	V-set and transmembrane domain-containing protein 1 isoform 3 precursor
NM_001288793.2	NP_001275722.1	V-set and transmembrane domain-containing protein 1 isoform 4
NM_198481.4	NP_940883.2	V-set and transmembrane domain-containing protein 1 isoform 1 precursor

VSTM1 Protein Structure

Ig_2

0
100
200
236 a.a.

Protein Preferred Names

Protein Names

V-set and transmembrane domain-containing protein 1

LAIR homolog

Recombinant VSTM1 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P71428	VSTM1 Protein, Human (119a.a, HEK293, His)	Q6UX27 (Y17-T135)	≥95%
HY-P77282	VSTM1 Protein, Human (HEK293, Fc)	Q6UX27 (M1-T135)	≥95%
HY-P77283	VSTM1 Protein, Human (135a.a, HEK293, His)	Q6UX27 (M1-T135)	≥95%

Related Diseases

Diseases

Alias

Hypothyroidism, Central, With Testicular Enlargement

X-Linked Central Congenital Hypothyroidism With Late-Onset Testicular Enlargement	CHTE
Hypothyroidism, Central, And Testicular Enlargement	Igsf1 Deficiency Syndrome
X-Linked Central Congenital Hypothyroidism With Late-Onset Macroorchidism	Central Hypothyroidism And Testicular Enlargement
Hypothyroidism, Central, Testicular Enlargement

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS15713	VSTM1 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	VSTM1	VGNC	VGNC:54001
Bos taurus	VSTM1	VGNC	VGNC:57056
Rattus norvegicus	VSTM1	RGD	RGD:2322891
Others	VSTM1	NCBI

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