P2RY8 - P2Y receptor family member 8 Gene

Homo sapiens

Also known as P2Y8

Gene ID: 286530 | Gene type: protein coding

About P2RY8

Cytogenetic location: Xp22.33 Genomic coordinates (GRCh38): X:1,462,581-1,537,185 (from NCBI)

This gene has 2 transcripts (splice variants), 163 orthologues, 16 paralogues and is associated with 46 phenotypes. Broad expression in lymph node (RPKM 13.9), spleen (RPKM 8.9) and 14 other tissues.

Summary

The protein encoded by this gene belongs to the family of G-protein coupled receptors, that are preferentially activated by adenosine and uridine nucleotides. This gene is moderately expressed in undifferentiated HL60 cells, and is located on both chromosomes X and Y. [provided by RefSeq, Jul 2008]

P2RY8 Products(1)

mRNA	Protein	Name
NM_178129.5	NP_835230.1	P2Y purinoceptor 8

P2RY8 Protein Structure

7tm_1

0
100
200
300
359 a.a.

Protein Preferred Names

Protein Names

P2Y purinoceptor 8

G-protein coupled purinergic receptor P2Y8

Related Diseases

Diseases

Alias

B-Lymphoblastic Leukemia/Lymphoma With Iamp21

B-All With Iamp21

Intrachromosomal Amplification Of Chromosome 21

Intellectual Developmental Disorder, Autosomal Dominant 33

MRD33	Autosomal Dominant Non-Syndromic Intellectual Disability 33
Mental Retardation, Autosomal Dominant 33	Autosomal Dominant Intellectual Developmental Disorder 33
Autosomal Dominant Mental Retardation 33	Mental Retardation, Autosomal Dominant, Type 33

Plasma Cell Neoplasm

Plasma Cell Dyscrasia	Paraproteinemias
Plasma Cell Tumour	Plasmacytic Tumor
Multiple Myeloma	Plasmacytoma
Plasma Cell Tumours	Plasma Cells Dyscrasia

Myeloma, Multiple

Multiple Myeloma	Plasma Cell Myeloma
Kahler Disease	Myelomatosis
Medullary Plasmacytoma	Multiple Myeloma, Resistance To
Myeloma	Plasma Cell Dyscrasia
Kahler'S Disease	Multiple Myeloma, Susceptibility To
Myeloma - Multiple	Kahler-Bozzolo Disease
Plasma Cell Myelomas	MM
Plasma Cell Neoplasm	Primary Systemic Amyloidosis
Primary Amyloidosis	Immunoglobulin Deposition Disease
Plasmacytic Myeloma	Multiple Myelomata
Multiple Myeloma Nos	Multiple Myeloma Without Mention Of Remission
Monostotic Plasma Cell Myeloma	Mm - [Multiple Myeloma]

B-Lymphoblastic Leukemia/Lymphoma With Etv6-Runx1

B-All With Etv6-Runx1	B-Lymphoblastic Leukemia/Lymphoma With T(12
21)(P13.2	Q22.1)
Etv6-Runx1	B Lymphoblastic Leukemia/Lymphoma With T(12
21)(P13.2	Q22.1)
Etv6-Runx1

Childhood B-Cell Acute Lymphoblastic Leukemia

B-Cell Childhood Acute Lymphoblastic Leukemia

Chromosomal Duplication Syndrome

B-Lymphoblastic Leukemia/Lymphoma

B Lymphoblastic Leukemia/Lymphoma	B-All
Precursor B Lymphoblastic Lymphoma/Leukemia	C-All
Lymphoblastic Lymphoma, Nos	Common Precursor B All
Lymphoblastic B-Cell Lymphoma	Pro-B All
B-Precursor Lymphoma	Lbl - [Lymphoblastic Lymphoma]

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS09937	P2RY8 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca fascicularis	P2RY8	NCBI
Mus musculus	P2RY8	NCBI

Name
Email *

	Sorry, but the email address you supplied was invalid.