P2RY8 - P2Y receptor family member 8 Gene

Also Known as P2Y8

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 286530

About P2RY8

Cytogenetic location: Xp22.33 Genomic coordinates (GRCh38): X:1,462,581-1,537,185 (from NCBI)

This gene has 2 transcripts (splice variants), 163 orthologues, 16 paralogues and is associated with 46 phenotypes. Broad expression in lymph node (RPKM 13.9), spleen (RPKM 8.9) and 14 other tissues.

Summary

The protein encoded by this gene belongs to the family of G-protein coupled receptors, that are preferentially activated by adenosine and uridine nucleotides. This gene is moderately expressed in undifferentiated HL60 cells, and is located on both chromosomes X and Y. [provided by RefSeq, Jul 2008]

P2RY8 Products (1)

mRNA Protein Name
NM_178129.5 NP_835230.1 P2Y purinoceptor 8

P2RY8 Protein Structure

7tm_1

7tm_1: 7 transmembrane receptor (rhodopsin family) (40 - 293)

  • 0
  • 100
  • 200
  • 300
  • 359 a.a.
Protein Preferred Names Protein Names

P2Y purinoceptor 8

  • G-protein coupled purinergic receptor P2Y8

P2RY8 Antibodies

Cat. No. Product Name Application Reactivity
HY-P84661 P2RY8 Antibody (YA4358) IHC-P, ICC/IF, FC, ELISA Human
HY-P84661A P2RY8 Antibody (YA4358)(PBS only) IHC-P, ICC/IF, FC, ELISA Human

Related Diseases

Diseases Alias
B-Lymphoblastic Leukemia/Lymphoma With Iamp21

  • B-All With Iamp21

  • Intrachromosomal Amplification Of Chromosome 21
Intellectual Developmental Disorder, Autosomal Dominant 33

  • MRD33

  • Autosomal Dominant Non-Syndromic Intellectual Disability 33

  • Mental Retardation, Autosomal Dominant 33

  • Autosomal Dominant Intellectual Developmental Disorder 33

  • Autosomal Dominant Mental Retardation 33

  • Mental Retardation, Autosomal Dominant, Type 33
Plasma Cell Neoplasm

  • Plasma Cell Dyscrasia

  • Paraproteinemias

  • Plasma Cell Tumour

  • Plasmacytic Tumor

  • Multiple Myeloma

  • Plasmacytoma

  • Plasma Cell Tumours

  • Plasma Cells Dyscrasia
Myeloma, Multiple

  • Multiple Myeloma

  • Plasma Cell Myeloma

  • Kahler Disease

  • Myelomatosis

  • Medullary Plasmacytoma

  • Multiple Myeloma, Resistance To

  • Myeloma

  • Plasma Cell Dyscrasia

  • Kahler'S Disease

  • Multiple Myeloma, Susceptibility To

  • Myeloma - Multiple

  • Kahler-Bozzolo Disease

  • Plasma Cell Myelomas

  • MM

  • Plasma Cell Neoplasm

  • Primary Systemic Amyloidosis

  • Primary Amyloidosis

  • Immunoglobulin Deposition Disease

  • Plasmacytic Myeloma

  • Multiple Myelomata

  • Multiple Myeloma Nos

  • Multiple Myeloma Without Mention Of Remission

  • Monostotic Plasma Cell Myeloma

  • Mm - [Multiple Myeloma]
B-Lymphoblastic Leukemia/Lymphoma With Etv6-Runx1

  • B-All With Etv6-Runx1

  • B-Lymphoblastic Leukemia/Lymphoma With T(12

  • 21)(P13.2

  • Q22.1)

  • Etv6-Runx1

  • B Lymphoblastic Leukemia/Lymphoma With T(12

  • 21)(P13.2

  • Q22.1)

  • Etv6-Runx1
Childhood B-Cell Acute Lymphoblastic Leukemia

  • B-Cell Childhood Acute Lymphoblastic Leukemia
Chromosomal Duplication Syndrome
B-Lymphoblastic Leukemia/Lymphoma

  • B Lymphoblastic Leukemia/Lymphoma

  • B-All

  • Precursor B Lymphoblastic Lymphoma/Leukemia

  • C-All

  • Lymphoblastic Lymphoma, Nos

  • Common Precursor B All

  • Lymphoblastic B-Cell Lymphoma

  • Pro-B All

  • B-Precursor Lymphoma

  • Lbl - [Lymphoblastic Lymphoma]
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09937 P2RY8 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-158813 S-Geranylgeranyl-L-glutathione Inhibitor / Unkown