Havcr1 - hepatitis A virus cellular receptor 1 Gene

Also Known as Kim1; KIM-1

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 286934

Summary

Predicted to enable phosphatidylserine binding activity and virus receptor activity. Involved in several processes, including phagocytosis, engulfment; response to mycotoxin; and response to testosterone. Located in several cellular components, including apical plasma membrane; cell surface; and phagocytic vesicle. Biomarker of colitis; hypertension; kidney failure (multiple); and proteinuria (multiple). Human ortholog(s) of this gene implicated in atopic dermatitis. Orthologous to human HAVCR1 (hepatitis A virus cellular receptor 1). [provided by Alliance of Genome Resources, Apr 2022]

Havcr1 Products (1)

mRNA Protein Name
NM_173149.2 NP_775172.1 hepatitis A virus cellular receptor 1 homolog precursor

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Verweise Source
involved in phagocytosis, engulfment IMP
IMP: Inferred from mutant phenotype
18414680 RGD
involved in response to mycotoxin IEP
IEP: Inferred from expression pattern
18308701 RGD
involved in response to nutrient IEP
IEP: Inferred from expression pattern
18815216 RGD
involved in response to testosterone IEP
IEP: Inferred from expression pattern
23552495 RGD
involved in response to xenobiotic stimulus IEP
IEP: Inferred from expression pattern
19535489 RGD
Cellular Component GO Annotation Evidence Verweise Source
located in apical plasma membrane IDA
IDA: Inferred from direct assay
16467126 RGD
located in cell surface IDA
IDA: Inferred from direct assay
19371613 RGD
located in extracellular space IDA
IDA: Inferred from direct assay
19522876 RGD
located in phagocytic vesicle IDA
IDA: Inferred from direct assay
18414680 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

hepatitis A virus cellular receptor 1 homolog

  • HAVcr-1

  • TIMD-1

  • kidney injury molecule 1

  • t cell immunoglobulin and mucin domain-containing protein 1

Recombinant Havcr1 Proteins

Art. -Nr. Produktname Accession Reinheit
HY-P73601 TIM-1/KIM-1/HAVCR Protein, Rat (HEK293, His-Fc) O54947/NP_775172.1 (S18-V238) ≥ 90%, as determined by reducing SDS-PAGE.
HY-P73602 TIM-1/KIM-1/HAVCR Protein, Rat (HEK293, His) O54947/NP_775172.1 (S18-V238) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-RS06021 HAVCR1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19510 Havcr1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26004 Havcr1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Havcr1 NCBI NCBI:26762