Eftud2 - elongation factor Tu GTP binding domain containing 2 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 287739

Summary

Predicted to enable GTPase activity and U5 snRNA binding activity. Involved in cellular response to xenobiotic stimulus and response to cocaine. Predicted to be located in Cajal body and nuclear speck. Predicted to be part of U2-type catalytic step 2 spliceosome; U2-type precatalytic spliceosome; and U4/U6 x U5 tri-snRNP complex. Predicted to be active in cytosol. Human ortholog(s) of this gene implicated in esophageal atresia and mandibulofacial dysostosis, Guion-Almeida type. Orthologous to human EFTUD2 (elongation factor Tu GTP binding domain containing 2). [provided by Alliance of Genome Resources, Apr 2022]

Eftud2 Products (2)

mRNA Protein Name
NM_001398598.1 NP_001385527.1 116 kDa U5 small nuclear ribonucleoprotein component isoform 1
NM_001398599.1 NP_001385528.1 116 kDa U5 small nuclear ribonucleoprotein component isoform 2

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in cellular response to xenobiotic stimulus IEP
IEP: Inferred from expression pattern
24793618 RGD
involved in response to cocaine IEP
IEP: Inferred from expression pattern
20187946 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

116 kDa U5 small nuclear ribonucleoprotein component

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04203 EFTUD2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21120 Eftud2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27639 Eftud2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Eftud2 NCBI NCBI:9343