Osm - oncostatin M Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 289747

Summary

Predicted to enable cytokine activity; growth factor activity; and oncostatin-M receptor binding activity. Predicted to be involved in several processes, including oncostatin-M-mediated signaling pathway; positive regulation of intracellular signal transduction; and positive regulation of macromolecule metabolic process. Predicted to act upstream of or within several processes, including positive regulation of protein phosphorylation; positive regulation of signal transduction; and tyrosine phosphorylation of STAT protein. Predicted to be located in extracellular space. Orthologous to human OSM (oncostatin M). [provided by Alliance of Genome Resources, Apr 2022]

Osm Products (1)

mRNA Protein Name
NM_001006961.2 NP_001006962.1 oncostatin-M precursor
Protein Preferred Names Protein Names

oncostatin-M

Related Agents

  • Approval
  • Clinical Phase
  • Pre-clinical Phase

Approval

Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P99590 Sotatercept 99.94% Unkown

Clinical Phase

Inhibitory Antibodies (2)
Cat. No. Product Name Effect
Purity Phase
HY-P99519 Vixarelimab Inhibitor 96.90% Phase 2
HY-P991051 GSK-2330811 Inhibitor 98.69% Phase 2

Pre-clinical Phase

Bioactive Molecules (13)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-33354 Nitrochin 99.92% Unkown
HY-148692 OSM-SMI-10B Inhibitor 99.70% Unkown
HY-175465 SMI-10B13 Inhibitor 99.30% Unkown
HY-162238 OSM-S-106 Inhibitor 99.34% Unkown
HY-148693 OSM-SMI-8 Antagonist / Unkown
HY-148693A (E/Z)-OSM-SMI-8 Antagonist / Unkown
HY-148692A (E/Z)-OSM-SMI-10B Inhibitor / Unkown
HY-148695B ADR58 sodium Inhibitor / Unkown
HY-148695C Truncated ADR58 sodium Inhibitor / Unkown
HY-RS02108 CCM2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS09850 OSM Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS16547 Osm Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22979 Osm Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P991333 GSK-315234 Inhibitor 98.16% Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Osm NCBI NCBI:5008