F11 - coagulation factor XI Gene

Also Known as LRRGT00086

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 290757

Summary

Enables serine-type Aminopeptidase activity. Involved in blood coagulation. Located in extracellular space. Human ortholog(s) of this gene implicated in Factor XI deficiency and thrombosis. Orthologous to human F11 (coagulation Factor XI). [provided by Alliance of Genome Resources, Apr 2022]

F11 Products (1)

mRNA Protein Name
NM_001411666.1 NP_001398595.1 coagulation factor XI precursor

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables serine-type aminopeptidase activity IDA
IDA: Inferred from direct assay
10899350 RGD
Cellular Component GO Annotation Evidence References Source
located in extracellular space IDA
IDA: Inferred from direct assay
10899350 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

coagulation factor XI

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Phase
HY-P991124 Cenvacibart Ligand 99% Phase 3

Pre-clinical Phase

Bioactive Molecules (16)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-162065 N6F11 Inducer 98.11% Unkown
HY-N0541 Pseudoginsenoside F11 99.87% Unkown
HY-124084A SW203668 TFA Inhibitor 99.79% Unkown
HY-N6650 Isotanshinone IIA 98.0% Unkown
HY-RS04626 F11R Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-114606 SW208108 Inhibitor / Unkown
HY-124084 SW203668 Inhibitor / Unkown
HY-19606 Cytogenin Inhibitor / Unkown
HY-RS03478 CYP4F11 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS04625 F11 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W143313 1,2-Heptanediol 98.0% Unkown
HY-RS17241 F11 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19600 F11r Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23695 F11 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26096 F11r Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W472509 11-HETE Activator / Unkown
Inhibitory Antibodies (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P991761 Anti-Mouse CXCL10 Antibody (1F11) Inhibitor 97.564% Unkown
HY-P991608 CTM01 Inhibitor / Unkown
HY-P991757 Anti-Human/Mouse/Rat/Canine/Swine PSMA Antibody (3F11) Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens F11 NCBI NCBI:2160