Klk6 - kallikrein related-peptidase 6 Gene

Also Known as Klni; Prss9

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 29245

Summary

Enables peptidase activity. Involved in regulation of neuron projection development. Predicted to be located in cytoplasm and extracellular region. Predicted to be active in secretory granule. Human ortholog(s) of this gene implicated in Alzheimer's disease; Lewy body dementia; Parkinson's disease; demyelinating disease; and multiple system atrophy. Orthologous to human KLK6 (Kallikrein related peptidase 6). [provided by Alliance of Genome Resources, Apr 2022]

Klk6 Products (1)

mRNA Protein Name
NM_019175.1 NP_062048.1 kallikrein-6 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Verweise Source
enables peptidase activity IDA
IDA: Inferred from direct assay
11802715 RGD
Biological Process GO Annotation Evidence Verweise Source
involved in regulation of neuron projection development IDA
IDA: Inferred from direct assay
16987227 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

kallikrein-6

  • kallikrein 6 (neurosin)

  • kallikrein 6 (neurosin, zyme)

  • kallikrein i

  • protease serine 9 (neurosin)

  • protease, serine, 9

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (8)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-124714 DKFZ-251 Inhibitor 95.93% Unkown
HY-124610 DKFZ-633 Inhibitor / Unkown
HY-182600 KLK6-IN-1 Inhibitor / Unkown
HY-RS07373 KLK1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS07384 KLK6 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17290 Klk6 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18037 Klk1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23745 Klk6 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Klk6 NCBI NCBI:5653