Sell - selectin L Gene

Also Known as A.11; LECAM-1; L-selectin

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 29259

Summary

Enables glycolipid binding activity. Involved in several processes, including positive regulation of neutrophil chemotaxis; response to fatty acid; and response to hyperoxia. Located in cell surface. Used to study colitis and peripheral vascular disease. Biomarker of abdominal aortic aneurysm; endometriosis; pancreatitis; and toxic shock syndrome. Human ortholog(s) of this gene implicated in Crohn's disease; IgA glomerulonephritis; and ulcerative colitis. Orthologous to human SELL (Selectin L). [provided by Alliance of Genome Resources, Apr 2022]

Sell Products (1)

mRNA Protein Name
NM_019177.4 NP_062050.3 L-selectin precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables glycolipid binding IDA
IDA: Inferred from direct assay
7678958 RGD
Biological Process GO Annotation Evidence References Source
involved in positive regulation of neutrophil chemotaxis IMP
IMP: Inferred from mutant phenotype
15677732 RGD
involved in regulation of apoptotic process IDA
IDA: Inferred from direct assay
18054560 RGD
involved in response to hyperoxia IEP
IEP: Inferred from expression pattern
12730074 RGD
involved in response to linoleic acid IEP
IEP: Inferred from expression pattern
20730605 RGD
involved in response to oleic acid IEP
IEP: Inferred from expression pattern
20730605 RGD
Cellular Component GO Annotation Evidence References Source
located in cell surface IDA
IDA: Inferred from direct assay
17177850 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

L-selectin

  • CD62 antigen-like family member L

  • LAM-1

  • LECAM1

  • leukocyte adhesion molecule 1

  • leukocyte-endothelial cell adhesion molecule 1

  • ly-22

  • lymph node homing receptor

  • lymphocyte antigen 22

  • lymphocyte surface MEL-14 antigen

  • selectin, lymphocyte

Recombinant Sell Proteins

Cat. No. Product Name Accession Purity
HY-P76638 L-Selectin/CD62L Protein, Rat (HEK293, His) P30836 (W39-N332) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS12646 SELL Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W036160 N-Fmoc-O-ethyl-L-homoserine / Unkown
HY-RS17751 Sell Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24218 Sell Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sell NCBI NCBI:6402