RPS6 - Rps6 ribosomal protein S6 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 29304

Summary

Enables mRNA binding activity. A structural constituent of ribosome. Involved in several processes, including cellular response to ethanol; negative regulation of bicellular tight junction assembly; and ribosomal small subunit assembly. Part of cytosolic small ribosomal subunit. Used to study transient cerebral ischemia. Biomarker of vascular dementia. Orthologous to human RPS6 (ribosomal protein S6). [provided by Alliance of Genome Resources, Apr 2022]

RPS6 Products (1)

mRNA Protein Name
NM_017160.1 NP_058856.1 40S ribosomal protein S6

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables mRNA binding IDA
IDA: Inferred from direct assay
7338522 RGD
enables structural constituent of ribosome IMP
IMP: Inferred from mutant phenotype
3378620 RGD
Biological Process GO Annotation Evidence References Source
involved in cellular response to ethanol IDA
IDA: Inferred from direct assay
15530665 RGD
involved in negative regulation of bicellular tight junction assembly IDA
IDA: Inferred from direct assay
25217631 RGD
involved in response to insulin IDA
IDA: Inferred from direct assay
17957382 RGD
involved in ribosomal small subunit assembly IMP
IMP: Inferred from mutant phenotype
3378620 RGD
Cellular Component GO Annotation Evidence References Source
is active in GABA-ergic synapse IDA
IDA: Inferred from direct assay
27764673 RGD
part of cytosolic small ribosomal subunit IDA
IDA: Inferred from direct assay
947902 RGD
is active in presynapse IDA
IDA: Inferred from direct assay
27764673 RGD
is active in ribosome IDA
IDA: Inferred from direct assay
27764673 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

40S ribosomal protein S6

  • 40S ribosomal protein S6-like

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (41)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-123919 TL13-112 Inhibitor 98.01% Unkown
HY-148065 FMF-06-098-1 Inhibitor 98.77% Unkown
HY-13495 ML281 98.04% Unkown
HY-122582 TL13-12 Degrader 98.16% Unkown
HY-148061 DB1113 99.86% Unkown
HY-148062 RSS0680 Degrader 99.85% Unkown
HY-148063 DB0614 99.92% Unkown
HY-W070306 PDK1-IN-1 Inhibitor 99.95% Unkown
HY-RS12247 RPS6 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-50733 CX-5011 free base / Unkown
HY-150643 RSK2-IN-2 Inhibitor / Unkown
HY-150717 RSK2-IN-3 Inhibitor / Unkown
HY-161874 RPS6-IN-1 / Unkown
HY-RS12248 RPS6KA1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS12249 Rps6ka1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS12250 Rps6ka1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS12251 RPS6KA2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS12252 Rps6ka2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS12253 Rps6ka2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS12254 RPS6KA3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS12255 Rps6ka3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS12256 Rps6ka3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS12257 RPS6KA4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS12258 RPS6KA5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS12259 RPS6KA6 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS12260 Rps6ka6 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS12261 Rps6ka6 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS12262 RPS6KB1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS12263 Rps6kb1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS12264 Rps6kb1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS12265 RPS6KB2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS12266 Rps6kb2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS12267 Rps6kb2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS12268 RPS6KC1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-183393 NVP-BHS345 Inhibitor / Unkown
HY-RS17694 Rps6 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22025 Rps6ka4 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22026 Rps6ka5 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24156 Rps6 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28543 Rps6ka4 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28544 Rps6ka5 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens RPS6 NCBI NCBI:6194