Vamp3 - vesicle-associated membrane protein 3 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 29528

Summary

Enables syntaxin-1 binding activity. Involved in protein-containing complex assembly. Located in apical plasma membrane; clathrin-coated vesicle membrane; and recycling endosome. Part of SNARE complex. Is integral component of synaptic vesicle membrane. Orthologous to human VAMP3 (vesicle associated membrane protein 3). [provided by Alliance of Genome Resources, Apr 2022]

Vamp3 Products (1)

mRNA Protein Name
NM_057097.2 NP_476438.1 vesicle-associated membrane protein 3

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables SNARE binding IPI
IPI: Inferred from physical interaction
7698987 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
9396746 RGD
enables syntaxin-1 binding IPI
IPI: Inferred from physical interaction
7698987 RGD
Biological Process GO Annotation Evidence References Source
involved in protein-containing complex assembly IDA
IDA: Inferred from direct assay
10051443 RGD
Cellular Component GO Annotation Evidence References Source
part of SNARE complex IDA
IDA: Inferred from direct assay
10051443 RGD
located in apical plasma membrane IDA
IDA: Inferred from direct assay
7573412 RGD
located in clathrin-coated vesicle membrane IDA
IDA: Inferred from direct assay
7573412 RGD
located in intracellular vesicle IDA
IDA: Inferred from direct assay
12737809 RGD
located in recycling endosome IDA
IDA: Inferred from direct assay
10468577 RGD
is active in synaptic vesicle membrane EXP
EXP: Inferred from Experiment
17110340 RGD
is active in synaptic vesicle membrane IDA
IDA: Inferred from direct assay
17110340 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

vesicle-associated membrane protein 3

  • CEB

  • VAMP-3

  • cellubrevin

  • synaptobrevin-3

Vamp3 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Cross
Vamp3 P63025 Bves Mus musculus Q9ES83
Pull Down
20057356
Cross
Vamp3 P63025 Bves Mus musculus Q9ES83
Anti Tag CoIP
20057356
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-P10809 VAMP Inhibitor 98.13% Phase 2

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15595 VAMP3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22908 Vamp3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29422 Vamp3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Vamp3 NCBI NCBI:9341