Pex2 - peroxisomal biogenesis factor 2 Gene

Also Known as Pxmp3

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 29534

Summary

Predicted to enable metal ion binding activity. Predicted to be involved in several processes, including fatty acid metabolic process; negative regulation of cell population proliferation; and protein destabilization. Predicted to act upstream of or within several processes, including bile acid biosynthetic process; Cholesterol homeostasis; and regulation of Cholesterol biosynthetic process. Located in peroxisomal membrane. Human ortholog(s) of this gene implicated in peroxisomal biogenesis disorder and peroxisome biogenesis disorder 5A. Orthologous to human PEX2 (peroxisomal biogenesis factor 2). [provided by Alliance of Genome Resources, Apr 2022]

Pex2 Products (4)

mRNA Protein Name
NM_001388504.1 NP_001375433.1 peroxisome biogenesis factor 2 isoform 1
NM_001388505.1 NP_001375434.1 peroxisome biogenesis factor 2 isoform 1
NM_001388506.1 NP_001375435.1 peroxisome biogenesis factor 2 isoform 2
NM_017234.2 NP_058930.2 peroxisome biogenesis factor 2 isoform 1

Gene Ontology

  • Cellular Component
Cellular Component GO Annotation Evidence References Source
located in peroxisomal membrane IDA
IDA: Inferred from direct assay
8035823 RGD
located in peroxisome IDA
IDA: Inferred from direct assay
14561759 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

peroxisome biogenesis factor 2

  • PAF-1

  • peroxin-2

  • peroxisomal membrane protein 3, 35 kDa

  • peroxisome assembly factor 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS10348 PEX2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21406 Pex2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27925 Pex2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pex2 NCBI NCBI:5828