Tlr6 - toll-like receptor 6 Gene

Rattus norvegicus

Gene ID: 305353 | Gene type: protein coding

About Tlr6

Primary_assembly 14: 43,362,164-43,375,685 forward strand.mRatBN7.2:CM026987.1

This gene has 3 transcripts (splice variants), 190 orthologues, 26 paralogues and is associated with 14 phenotypes. Biased expression in Spleen (RPKM 83.7), Thymus (RPKM 35.7) and 9 other tissues.

Summary

Enables Lipopeptide binding activity. Involved in several processes, including microglial cell activation; nitric oxide metabolic process; and response to Bacterial lipoprotein. Predicted to be located in Golgi apparatus and membrane raft. Predicted to be part of Toll-like Receptor 2-Toll-like receptor 6 protein complex. Predicted to be integral component of plasma membrane. Used to study Bacterial pneumonia. Biomarker of perinatal necrotizing enterocolitis. Human ortholog(s) of this gene implicated in aspergillosis; asthma; infective endocarditis; rhinitis; and tuberculosis. Orthologous to human TLR6 (toll like receptor 6). [provided by Alliance of Genome Resources, Apr 2022]

Tlr6 Products(1)

mRNA	Protein	Name
NM_207604.1	NP_997487.1	toll-like receptor 6

Tlr6 Protein Structure

LRR_RI

PLN00113

PPP1R42

LRR_1

LRR_RI

PRK15370

LRR_RI

LRRCT

TIR

0
200
400
600
806 a.a.

Protein Preferred Names

Protein Names

toll-like receptor 6

Related Agents

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-P2036A	FSL-1 TFA	Agonist	99.76%	Unkown
HY-P2036	FSL-1	Agonist	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Tlr6	NCBI	NCBI:10333

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