EHD4 - EH domain containing 4 Gene

Homo sapiens

Also known as PAST4

Gene ID: 30844 | Gene type: protein coding

About EHD4

Cytogenetic location: 15q15.1 Genomic coordinates (GRCh38): 15:41,895,933-41,972,557 (from NCBI)

This gene has 2 transcripts (splice variants), 205 orthologues and 10 paralogues. Ubiquitous expression in urinary bladder (RPKM 15.6), gall bladder (RPKM 14.3) and 25 other tissues.

Summary

Enables cadherin binding activity. Involved in endocytic recycling and protein homooligomerization. Located in endoplasmic reticulum and recycling endosome membrane. [provided by Alliance of Genome Resources, Apr 2022]

EHD4 Products(1)

mRNA	Protein	Name
NM_139265.4	NP_644670.1	EH domain-containing protein 4

EHD4 Protein Structure

Dynamin_N

EF-hand_4

0
100
200
300
400
500
541 a.a.

Protein Preferred Names

Protein Names

EH domain-containing protein 4

PAST homolog 4

Related Diseases

Diseases

Alias

Ovarian Endometrial Cancer

Endometrioid Neoplasm Of Ovary	Malignant Ovarian Endometrioid Tumor
Ovarian Endometrioid Neoplasm

Cerebral Creatine Deficiency Syndrome 3

Arginine:Glycine Amidinotransferase Deficiency	Agat Deficiency
Gatm Deficiency	Creatine Deficiency Syndrome Due To Agat Deficiency
L-Arginine:Glycine Amidinotransferase Deficiency	CCDS3
L-Arginine:Glycine Aminidotransferase Deficiency	Deficiency, Cerebral Creatine, Syndrome, Type 3

Hepatocellular Carcinoma

Liver Cancer	Primary Liver Cancer
HCC	Hepatoma
Malignant Neoplasm Of Liver	Liver Neoplasms
Cancer, Hepatocellular	Liver Cell Carcinoma
Lcc	Hepatoblastoma, Somatic
Hepatic Cancer	Primary Malignant Neoplasm Of Liver
Rare Tumor Of Liver And Intrahepatic Biliary Tract	Hepatocellular Carcinoma, Somatic
Hepatocellular Carcinoma, Childhood Type, Somatic	Hepatocellular Cancer, Somatic
Ca Liver - Primary	Hepatic Neoplasm
Malignant Hepato-Biliary Neoplasm	Malignant Neoplasm Of Liver, Not Specified As Primary Or Secondary
Malignant Neoplasm Of Liver, Primary	Malignant Tumor Of Liver
Neoplasm Of Liver	Non-Resectable Primary Hepatic Malignant Neoplasm
Resectable Malignant Neoplasm Of Liver	Resectable Malignant Neoplasm Of The Liver
Primary Liver Carcinoma	Primary Malignant Liver Neoplasm
Primary Cancer Of Liver	Primary Tumor Of The Liver
Rare Tumor Of Liver And Ibt	Hepatocellular Cancer
Neoplasm Of The Liver	Carcinoma, Hepatocellular
Hepatomas	Liver Neoplasm
Liver Carcinoma	Liver And Intrahepatic Biliary Tract Carcinoma
Malignant Hepatobiliary Neoplasm	Adult Primary Hepatocellular Carcinoma
Hepatoblastoma	Carcinoma Of Liver
Malignant Liver Tumour	Malignant Hepatic Tumour

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS04224	EHD4 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	EHD4	VGNC	VGNC:28374
Mus musculus	EHD4	MGD	MGI:1919619
Felis catus	EHD4	VGNC	VGNC:104385
Macaca mulatta	EHD4	VGNC	VGNC:72177
Rattus norvegicus	EHD4	RGD	RGD:628883
Canis familiaris	EHD4	VGNC	VGNC:40248