Xpc - XPC complex subunit, DNA damage recognition and repair factor Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 312560

Summary

Predicted to enable DNA binding activity; RNA polymerase II-specific DNA-binding transcription factor binding activity; and transcription coactivator activity. Involved in response to auditory stimulus and response to xenobiotic stimulus. Located in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in pancreatic cancer; serous cystadenocarcinoma; xeroderma pigmentosum; and xeroderma pigmentosum group C. Orthologous to human XPC (XPC complex subunit, DNA damage recognition and repair factor). [provided by Alliance of Genome Resources, Apr 2022]

Xpc Products (1)

mRNA Protein Name
NM_001107874.1 NP_001101344.1 DNA repair protein complementing XP-C cells

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in response to auditory stimulus IEP
IEP: Inferred from expression pattern
23022597 RGD
involved in response to xenobiotic stimulus IEP
IEP: Inferred from expression pattern
19297277 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

DNA repair protein complementing XP-C cells

  • xeroderma pigmentosum, complementation group C

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (6)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-157786 XPC-5462 Inhibitor 99.65% Unkown
HY-157784 XPC-7724 Inhibitor 99.46% Unkown
HY-128772 XPC-6444 Inhibitor 98.93 Unkown
HY-RS15885 XPC Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20245 Xpc Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26753 Xpc Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Xpc NCBI NCBI:7508