Gpr68 - G protein-coupled receptor 68 Gene
Species: Rattus norvegicus
About Gpr68
This gene has 4 transcripts (splice variants), 197 orthologues, 1 paralogue and is associated with 3 phenotypes. Biased expression in Thymus (RPKM 47.3), Spleen (RPKM 36.6) and 9 other tissues.
Summary
Predicted to enable G protein-coupled receptor activity. Predicted to be involved in cellular response to pH. Predicted to act upstream of or within negative regulation of monocyte differentiation; positive regulation of Insulin secretion involved in cellular response to glucose stimulus; and positive regulation of osteoclast development. Predicted to be integral component of membrane. Human ortholog(s) of this gene implicated in amelogenesis imperfecta type 2A6. Orthologous to human GPR68 (G protein-coupled receptor 68). [provided by Alliance of Genome Resources, Apr 2022]
Gpr68 Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_001108049.1 | NP_001101519.1 | ovarian cancer G-protein coupled receptor 1 |
Gpr68 Protein Structure
7tmA_GPR68_OGR1: cd15367 (31 - 306)
7tmA_GPR68_OGR1: cd15367 (31 - 58)
7tmA_GPR68_OGR1: cd15367 (65 - 90)
7tmA_GPR68_OGR1: cd15367 (103 - 133)
7tmA_GPR68_OGR1: cd15367 (145 - 167)
7tmA_GPR68_OGR1: cd15367 (191 - 220)
7tmA_GPR68_OGR1: cd15367 (230 - 260)
7tmA_GPR68_OGR1: cd15367 (274 - 299)
- 0
- 100
- 200
- 300
- 375 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
ovarian cancer G-protein coupled receptor 1 |
|
Related Agents
- Pre-clinical Phase
Pre-clinical Phase
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-154954 | Ogremorphin | Inhibitor | 99.60% | Unkown |
| HY-110279 | Ogerin | Modulator | 99.94% | Unkown |
| HY-134494 | MS48107 | 99.90% | Unkown | |
| HY-105791S | Sulazepam-d5 | Activator | / | Unkown |
| HY-169704 | Ogerin analogue 1 | Control | / | Unkown |
| HY-181485 | GPR68 antagonist 1 | Antagonist | / | Unkown |
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