2. Gene
  3. VSIG1 - V-set and immunoglobulin domain containing 1 Gene

VSIG1 - V-set and immunoglobulin domain containing 1 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as GPA34; dJ889N15.1; 1700062D20Rik

Gene ID: 340547 | Gene type: protein coding

About VSIG1

Cytogenetic location: Xq22.3 Genomic coordinates (GRCh38): X:108,018,879-108,079,184 (from NCBI)

This gene has 5 transcripts (splice variants), 164 orthologues and 14 paralogues. Biased expression in stomach (RPKM 88.2), testis (RPKM 34.6) and 1 other tissue.

Summary

This gene encodes a member of the junctional adhesion molecule (JAM) family. The encoded protein contains multiple glycosylation sites at the N-terminal region, and multiple phosphorylation sites and glutamic acid/proline (EP) repeats at the C-terminal region. The gene is expressed in normal stomach and testis, as well as in gastric, esophageal and ovarian cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009]

VSIG1 Products(2)

mRNA Protein Name
NM_001170553.2 NP_001164024.1 V-set and immunoglobulin domain-containing protein 1 isoform 1 precursor
NM_182607.5 NP_872413.1 V-set and immunoglobulin domain-containing protein 1 isoform 2 precursor

VSIG1 Protein Structure

V-set

V-set: Immunoglobulin V-set domain (23 - 129)

Ig_2

Ig_2: Immunoglobulin domain (151 - 227)

  • 0
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  • 300
  • 387 a.a.
Protein Preferred Names Protein Names

V-set and immunoglobulin domain-containing protein 1

cell surface A33 antigen

Recombinant VSIG1 Proteins

Cat. No. Product Name Accession Purity
HY-P71675 VSIG1 Protein, Human (HEK293, His) Q86XK7 (22V-232E) ≥95%

Related Diseases

Diseases Alias
Mucinous Lung Adenocarcinoma
Ovarian Cystadenoma

Cystoma Serosum Simplex

Simple Cystoma Of Ovary

Simple Cystoma Of The Ovary
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS15706 VSIG1 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus VSIG1 MGD MGI:1926039
Canis familiaris VSIG1 VGNC VGNC:54610
Bos taurus VSIG1 VGNC VGNC:56959
Rattus norvegicus VSIG1 RGD RGD:1565570
Felis catus VSIG1 VGNC VGNC:66976
Macaca mulatta VSIG1 VGNC VGNC:79734
Others VSIG1 NCBI