NCKAP5 - NCK associated protein 5 Gene

Also Known as NAP5; ERIH1; ERIH2

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 344148

About NCKAP5

Cytogenetic location: 2q21.2 Genomic coordinates (GRCh38): 2:132,671,788-133,674,836 (from NCBI)

This gene has 7 transcripts (splice variants), 222 orthologues and 1 paralogue. Broad expression in lung (RPKM 2.7), kidney (RPKM 0.7) and 20 other tissues.

Summary

Predicted to be involved in microtubule bundle formation and microtubule depolymerization. Predicted to be active in microtubule plus-end. [provided by Alliance of Genome Resources, Apr 2022]

NCKAP5 Products (2)

mRNA Protein Name
NM_207363.3 NP_997246.2 nck-associated protein 5 isoform 1
NM_207481.4 NP_997364.3 nck-associated protein 5 isoform 2

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
17474147 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

NCKAP5 Protein Structure

NCKAP5

NCKAP5: Nck-associated protein 5, Peripheral clock protein (1467 - 1776)

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  • 1909 a.a.
Protein Preferred Names Protein Names

nck-associated protein 5

  • NAP-5

NCKAP5 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
NCKAP5 O14513 NCK1 Homo sapiens P16333
Anti Tag CoIP
33961781
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09084 NCKAP5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS09085 NCKAP5L Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris NCKAP5 VGNC VGNC:43654
Felis catus NCKAP5 VGNC VGNC:63738
Bos taurus NCKAP5 VGNC VGNC:56130
Rattus norvegicus NCKAP5 RGD RGD:1564507
Mus musculus NCKAP5 MGD MGI:2686394
Macaca mulatta NCKAP5 VGNC VGNC:104544
Others NCKAP5 NCBI