Ncor2 - nuclear receptor co-repressor 2 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 360801

Summary

Enables chromatin binding activity; Glucocorticoid Receptor binding activity; and retinoid X receptor binding activity. Involved in several processes, including estrous cycle; lactation; and response to estradiol. Located in chromatin and nucleus. Human ortholog(s) of this gene implicated in osteoarthritis. Orthologous to human NCOR2 (nuclear receptor corepressor 2). [provided by Alliance of Genome Resources, Apr 2022]

Ncor2 Products (1)

mRNA Protein Name
NM_001108334.1 NP_001101804.1 nuclear receptor corepressor 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables chromatin binding IDA
IDA: Inferred from direct assay
15870285 RGD
enables nuclear glucocorticoid receptor binding IPI
IPI: Inferred from physical interaction
15870285 RGD
enables nuclear receptor binding IPI
IPI: Inferred from physical interaction
15870285 RGD
enables nuclear retinoic acid receptor binding IPI
IPI: Inferred from physical interaction
15234273 RGD
enables nuclear retinoid X receptor binding IPI
IPI: Inferred from physical interaction
15234273 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
15870285 RGD
enables protein-containing complex binding IPI
IPI: Inferred from physical interaction
17356170 RGD
Biological Process GO Annotation Evidence References Source
involved in cerebellum development IEP
IEP: Inferred from expression pattern
10803578 RGD
involved in estrous cycle IEP
IEP: Inferred from expression pattern
15862975 RGD
involved in lactation IEP
IEP: Inferred from expression pattern
15946693 RGD
involved in response to estradiol IEP
IEP: Inferred from expression pattern
9564863 RGD
Cellular Component GO Annotation Evidence References Source
located in chromatin IDA
IDA: Inferred from direct assay
17456789 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

nuclear receptor corepressor 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-173033 MI-883 99.57% Unkown
HY-P3364A Ac-QPKK(Ac)-AMC acetate Substrate 99.38% Unkown
HY-RS09097 NCOR2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19464 Ncor2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25957 Ncor2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ncor2 NCBI NCBI:9612