Cbfb - core-binding factor subunit beta Gene

Also Known as Pebp2

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 361391

Summary

Enables DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II; protein polyubiquitination; and regulation of alpha-beta T cell differentiation. Predicted to act upstream of or within several processes, including hemopoiesis; osteoblast differentiation; and positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of core-binding activity factor complex. Human ortholog(s) of this gene implicated in acute myeloid leukemia. Orthologous to human CBFB (core-binding factor subunit beta). [provided by Alliance of Genome Resources, Apr 2022]

Cbfb Products (1)

mRNA Protein Name
NM_001013191.1 NP_001013209.1 core-binding factor subunit beta

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables DNA binding IDA
IDA: Inferred from direct assay
9930766 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

core-binding factor subunit beta

  • core binding factor beta

  • core-binding factor, beta subunit

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (10)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-108470 Ro5-3335 Inhibitor 99.52% Unkown
HY-RS01995 CBFB Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-124137 Runx1-CBFβ interaction inhibitor 1 Inhibitor / Unkown
HY-RS09271 NFYA Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS09272 NFYB Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-174541 Human RUNX1 mRNA / Unkown
HY-RS18748 Cbfb Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20307 Nfya Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25235 Cbfb Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26815 Nfya Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cbfb NCBI NCBI:865