Ikbke - inhibitor of nuclear factor kappa B kinase subunit epsilon Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 363984

About Ikbke

Primary_assembly 13: 42,712,159-42,737,143 reverse strand.mRatBN7.2:CM026986.1

This gene has 1 transcript (splice variant), 199 orthologues, 3 paralogues and is associated with 3 phenotypes. Biased expression in Thymus (RPKM 144.4), Spleen (RPKM 1.1) and 9 other tissues.

Summary

Predicted to enable several functions, including IkappaB kinase activity; K48-linked polyubiquitin modification-dependent protein binding activity; and NF-kappaB-inducing kinase activity. Predicted to be involved in several processes, including interleukin-17-mediated signaling pathway; positive regulation of signal transduction; and regulation of RNA metabolic process. Predicted to be located in PML body and mitochondrial membrane. Predicted to be active in cytoplasm. Orthologous to human IKBKE (inhibitor of nuclear factor kappa B kinase subunit epsilon). [provided by Alliance of Genome Resources, Apr 2022]

Ikbke Products (1)

mRNA Protein Name
NM_001108854.1 NP_001102324.1 inhibitor of nuclear factor kappa-B kinase subunit epsilon

Ikbke Protein Structure

PKc_like

PKc_like: cl21453 (14 - 329)

Ubl_IKKE

Ubl_IKKE: cd17128 (307 - 382)

TBK1_CCD1

TBK1_CCD1: cl39732 (401 - 647)

  • 0
  • 200
  • 400
  • 600
  • 719 a.a.
Protein Preferred Names Protein Names

inhibitor of nuclear factor kappa-B kinase subunit epsilon

  • inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon

  • inhibitor of kappaB kinase epsilon

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-D0162 Malachite green hemioxalate 98.0% Unkown
HY-RS06661 IKBKE Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS06662 Ikbke Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS06663 Ikbke Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ikbke NCBI NCBI:9641