Bst2 - bone marrow stromal cell antigen 2 Gene

Also Known as Damp1; DAMP-1

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 378947

Summary

Predicted to enable metalloendopeptidase inhibitor activity and protein homodimerization activity. Involved in regulation of actin Cytoskeleton organization. Located in apical plasma membrane and cell surface. Human ortholog(s) of this gene implicated in acquired immunodeficiency syndrome and endometrial Cancer. Orthologous to human BST2 (bone marrow stromal cell antigen 2). [provided by Alliance of Genome Resources, Apr 2022]

Bst2 Products (1)

mRNA Protein Name
NM_198134.3 NP_937767.1 bone marrow stromal antigen 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
19273615 RGD
Biological Process GO Annotation Evidence References Source
involved in regulation of actin cytoskeleton organization IMP
IMP: Inferred from mutant phenotype
19273615 RGD
Cellular Component GO Annotation Evidence References Source
located in apical plasma membrane IDA
IDA: Inferred from direct assay
12956872 RGD
located in cell surface IDA
IDA: Inferred from direct assay
19273615 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

bone marrow stromal antigen 2

  • BST-2

  • protein DAMP-1

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-125900 Neocarzilin A 95.82% Phase 2

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01649 BST2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17448 Bst2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23904 Bst2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P990276 Anti-Mouse CD317/BST2 Antibody (927) Inhibitor ≥95.0% Unkown
HY-P991885 Anti-CD317 Antibody (HM1.24 ) / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Bst2 NCBI NCBI:684