CENPW - centromere protein W Gene

Homo sapiens

Also known as CUG2; CENP-W; C6orf173

Gene ID: 387103 | Gene type: protein coding

About CENPW

Cytogenetic location: 6q22.32 Genomic coordinates (GRCh38): 6:126,340,115-126,483,320 (from NCBI)

This gene has 3 transcripts (splice variants) and 124 orthologues. Broad expression in bone marrow (RPKM 2.8), testis (RPKM 2.0) and 20 other tissues.

Summary

Predicted to enable DNA binding activity and protein heterodimerization activity. Involved in chromosome segregation; kinetochore assembly; and mitotic cell cycle. Located in kinetochore and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

CENPW Products(3)

mRNA	Protein	Name
NM_001012507.4	NP_001012525.1	centromere protein W isoform b
NM_001286524.2	NP_001273453.1	centromere protein W isoform a
NM_001286525.2	NP_001273454.1	centromere protein W isoform c

CENPW Protein Structure

CENP-W

0
88 a.a.

Protein Preferred Names

Protein Names

centromere protein W

cancer-up-regulated gene 2 protein

Related Diseases

Diseases

Alias

Acromesomelic Dysplasia 2b

Fibular Hypoplasia And Complex Brachydactyly	Du Pan Syndrome
AMD2B	Dupans
Acromesomelic Dysplasia-2b	Fibular Aplasia-Complex Brachydactyly Syndrome

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS02494	CENPW Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	CENPW	VGNC	VGNC:60763
Mus musculus	CENPW	MGD	MGI:1913561
Rattus norvegicus	CENPW	RGD	RGD:1593465
Canis familiaris	CENPW	VGNC	VGNC:39114
Bos taurus	CENPW	VGNC	VGNC:27187
Macaca mulatta	CENPW	VGNC	VGNC:71071

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