Btla - B and T lymphocyte associated Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 407756

Summary

Predicted to enable signaling receptor activity. Predicted to be involved in immune response-regulating cell surface receptor signaling pathway. Predicted to act upstream of or within cell surface receptor signaling pathway; negative regulation of B cell proliferation; and negative regulation of alpha-beta T cell proliferation. Predicted to be located in external side of plasma membrane. Predicted to be integral component of plasma membrane. Orthologous to human BTLA (B and T lymphocyte associated). [provided by Alliance of Genome Resources, Apr 2022]

Btla Products (1)

mRNA Protein Name
NM_213630.2 NP_998795.2 B- and T-lymphocyte attenuator precursor
Protein Preferred Names Protein Names

B- and T-lymphocyte attenuator

  • B- and T-lymphocyte-associated protein

Recombinant Btla Proteins

Cat. No. Product Name Accession Purity
HY-P75466 BTLA/CD272 Protein, Rat (HEK293, mFc) Q6PNM1 (K30-Y183) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Inhibitory Antibodies (2)
Cat. No. Product Name Effect
Purity Phase
HY-P99961 Tifcemalimab Inhibitor 96.02% Phase 3
HY-P990773 Venanprubart Inhibitor 98.00% Phase 2

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-159885 MG-B-28 Inhibitor / Unkown
HY-P10851 HVEM(14-39) Inducer / Unkown
HY-RS01669 BTLA Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS16938 Btla Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23381 Btla Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P990298 Anti-Mouse BTLA/CD272 Antibody (6A6) Inhibitor 95.00% Unkown
HY-P991038 Zadoprubart 99% Unkown
HY-P991833 Anti-Mouse BTLA/CD272 Antibody (PK18.6) Inhibitor / Unkown
HY-P991835 Anti-Mouse BTLA/CD272 Antibody (PJ196) Inhibitor / Unkown
HY-P992182 ANB032 / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Btla NCBI NCBI:151888