ART3 - ADP-ribosyltransferase 3 (inactive) Gene

Also Known as ARTC3

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 419

About ART3

Cytogenetic location: 4q21.1 Genomic coordinates (GRCh38): 4:76,011,190-76,112,786 (from NCBI)

This gene has 17 transcripts (splice variants), 582 orthologues and 3 paralogues. Biased expression in testis (RPKM 18.7) and heart (RPKM 6.2).

Summary

This gene encodes an arginine-specific ADP-ribosyltransferase. The encoded protein catalyzes a reversible reaction which modifies proteins by the addition or removal of ADP-ribose to an arginine residue to regulate the function of the modified protein. An ADP-ribosyltransferase pseudogene is located on chromosome 11. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]

ART3 Products (16)

mRNA Protein Name
NM_001130016.3 NP_001123488.1 ecto-ADP-ribosyltransferase 3 isoform a precursor
NM_001130017.3 NP_001123489.1 ecto-ADP-ribosyltransferase 3 isoform c precursor
NM_001179.6 NP_001170.2 ecto-ADP-ribosyltransferase 3 isoform b precursor
NM_001377173.1 NP_001364102.1 ecto-ADP-ribosyltransferase 3 isoform d precursor
NM_001377174.1 NP_001364103.1 ecto-ADP-ribosyltransferase 3 isoform l precursor
NM_001377175.1 NP_001364104.1 ecto-ADP-ribosyltransferase 3 isoform c precursor
NM_001377176.1 NP_001364105.1 ecto-ADP-ribosyltransferase 3 isoform e precursor
NM_001377177.1 NP_001364106.1 ecto-ADP-ribosyltransferase 3 isoform f precursor
NM_001377178.1 NP_001364107.1 ecto-ADP-ribosyltransferase 3 isoform f precursor
NM_001377179.1 NP_001364108.1 ecto-ADP-ribosyltransferase 3 isoform g precursor
NM_001377180.1 NP_001364109.1 ecto-ADP-ribosyltransferase 3 isoform h precursor
NM_001377181.1 NP_001364110.1 ecto-ADP-ribosyltransferase 3 isoform i precursor
NM_001377182.1 NP_001364111.1 ecto-ADP-ribosyltransferase 3 isoform i precursor
NM_001377183.1 NP_001364112.1 ecto-ADP-ribosyltransferase 3 isoform j precursor
NM_001377184.1 NP_001364113.1 ecto-ADP-ribosyltransferase 3 isoform j precursor
NM_001377185.1 NP_001364114.1 ecto-ADP-ribosyltransferase 3 isoform k precursor

ART3 Protein Structure

ART

ART: NAD:arginine ADP-ribosyltransferase (29 - 252)

  • 0
  • 100
  • 200
  • 300
  • 389 a.a.
Protein Preferred Names Protein Names

ecto-ADP-ribosyltransferase 3

  • ADP-ribosyltransferase C2 and C3 toxin-like 3

Recombinant ART3 Proteins

Cat. No. Product Name Accession Purity
HY-P74409 ART3 Protein, Human (HEK293, His) AAH08397 (E27-S362) ≥ 90%, as determined by reducing SDS-PAGE.

Related Diseases

Diseases Alias
Lumbosacral Lipoma
Hypermobility Of Coccyx

  • Coccygeal Hypermobility Syndrome

  • Hypermobility Of The Coccyx
Afferent Loop Syndrome

  • Afferent Limb Syndrome
Klippel-Feil Syndrome 3
Placenta Praevia

  • Placenta Previa

  • Haemorrhage From Placenta Previa

  • Placenta Previa Haemorrhage

  • Lateral Placenta

  • Low Implantation Of Placenta Nos Or With Haemorrhage

  • Total Placenta Previa

  • Total Placenta Praevia Nos Or With Haemorrhage

  • Placental Previa Haemorrhage

  • Pp - [Placenta Previa]

  • Placenta Previa Marginalis

  • Placenta Previa Partialis

  • Partial Placenta Previa

  • Placenta Previa Centralis

  • Low Implantation Of Placenta

  • Low Implantation Or Insertion Of Placenta

  • Low Insertion Of Placenta

  • Low Lying Placenta

  • Marginal Placenta

  • Marginal Placenta Praevia Nos Or With Haemorrhage

  • Marginal Placenta Previa

  • Marginal Placental Haemorrhage

  • Partial Placenta Praevia Nos Or With Haemorrhage
Kummell'S Disease

  • Traumatic Spondylopathy

  • Kummell Disease

  • Kummell'S Spondylitis

  • Kümmelll-Verneuil Disease

  • Kümmell Spondylitis

  • Kümmell Disease

  • Traumatic Spondylosis
Brown-Sequard Syndrome

  • Brown-Squard Syndrome

  • Hemicord Syndrome

  • Hemiparaplegic Syndrome

  • Hemispinal Cord Syndrome

  • Brown-Séquard Syndrome
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01045 ART3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20253 Art3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26761 Art3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus ART3 MGD MGI:1202729
Rattus norvegicus ART3 RGD RGD:628833
Felis catus ART3 VGNC VGNC:68318
Bos taurus ART3 VGNC VGNC:26180
Canis familiaris ART3 VGNC VGNC:38148
Macaca mulatta ART3 VGNC VGNC:70025
Others ART3 NCBI