2. Gene
  3. PIK3CA - phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Gene

PIK3CA - phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Canis lupus familiaris (sub-species: familiaris)
Gene ID: 488084 | Gene type: protein coding

About PIK3CA

Primary_assembly 34: 12,497,011-12,573,751 forward strand.ROS_Cfam_1.0:CM025133.1

This gene has 1 transcript (splice variant), 275 orthologues and 9 paralogues.

PIK3CA Products(3)

mRNA Protein Name
XM_038445588.1 XP_038301516.1 phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
XM_038445587.1 XP_038301515.1 phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
XM_038445589.1 XP_038301517.1 phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

PIK3CA Protein Structure

PI3K_p85B

PI3K_p85B: pfam02192 (31 - 106)

PI3K_rbd

PI3K_rbd: smart00144 (172 - 291)

C2_PI3K_class_I_alpha

C2_PI3K_class_I_alpha: cd08398 (324 - 483)

PI3Ka_I

PI3Ka_I: cd00872 (524 - 695)

PI3Kc_IA_alpha

PI3Kc_IA_alpha: cd05175 (694 - 1063)

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  • 1068 a.a.
Protein Preferred Names Protein Names

phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

phosphoinositide-3-kinase, catalytic, alpha polypeptide

Related Agents

Approval
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-15244 Alpelisib 99.95% Yes
HY-15244R Alpelisib (Standard) 99.86% Unkown
Clinical Phase
Bioactive Molecules (6)
Cat. No. Product Name Effect
Purity Phase
HY-13898 Taselisib Inhibitor 99.75% Phase 3
HY-10358 MK-2206 dihydrochloride 99.99% Phase 1
HY-100886 BAY1082439 99.35% Phase 1
HY-126077 MTI-31 Inhibitor 99.98% Phase 1
HY-137849 RK-582 Inhibitor 98.05% Phase 1
HY-10358R MK-2206 dihydrochloride (Standard) / Phase 1
Pre-clinical Phase
Bioactive Molecules (14)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-108232 MK-2206 99.72% Unkown
HY-153306 Zovegalisib Inhibitor 98.80% Unkown
HY-137458A Vevorisertib trihydrochloride Inhibitor 99.13% Unkown
HY-137458 Vevorisertib Inhibitor 98.03% Unkown
HY-RS10523 PIK3CA Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-100424 PI3K-IN-63 Inhibitor / Unkown
HY-138302 PF-06862309 / Unkown
HY-172964 KIM-161 / Unkown
HY-183285 PI3Kα-IN-32 Inhibitor / Unkown
HY-183770 LCI40 Inhibitor / Unkown
HY-N12726 Halociline Inhibitor / Unkown
HY-RS10524 Pik3ca Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS10525 Pik3ca Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-116191 WJD008 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens PIK3CA NCBI NCBI:5290